An efficient one-pot synthesis of polyphenolic amino acids and evaluation of their radical-scavenging activity.
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DOI: 10.1016/j.bioorg.2019.102983
Abstract: A simple and efficient procedure for the synthesis of N-acyl 4-hydroxy, 4-hydroxy-3-methoxy and 3,4-dihydroxy phenylglycine amides by a strategy based on the multicomponent Ugi reaction is proposed. Hydroxybenzaldehyde derivatives were reacted with 4-methoxybenzylamine, cyclohexyl isocyanide… read more here.
Keywords: scavenging activity; polyphenolic amino; radical scavenging; acid ... See more keywords