Effects of a Polypill, Aspirin, and the Combination of Both on Cognitive and Functional Outcomes: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.5088
Abstract: Importance Vascular risk factors are associated with cognitive decline but studies addressing individual risk factors have not demonstrated an effect of risk factor management on the preservation of cognition. Few trials have examined the effect… read more here.
Keywords: decline; cognitive functional; risk; randomized clinical ... See more keywords
3D Printing of Four-in-One Oral Polypill with Multiple Release Profiles for Personalized Delivery of Caffeine and Vitamin B Analogues.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120360
Abstract: Personalized supplementation has found recent momentum with an estimated global market size of USD 1.6 billion in 2019 and an expected CAGR of 8.5% between 2020 - 2028. Alongside this rising trend, a simple, accurate,… read more here.
Keywords: vitamin analogues; release profiles; polypill; four one ... See more keywords
Real-life effect on the control of risk factors associated with initiation of the cardiovascular polypill created from equipotent drugs.
Sign Up to like & getrecommendations! Published in 2021 at "Revista clinica espanola"
DOI: 10.1016/j.rceng.2021.05.008
Abstract: OBJECTIVE This work aims to analyze the impact of Spain's National Center for Cardiovascular Research (CNIC-Ferrer)'s cardiovascular (CV)-polypill on blood pressure (BP) and low-density lipoprotein cholesterol (cLDL) levels in patients in our healthcare area who… read more here.
Keywords: initiation; cardiovascular polypill; equally potent; polypill ... See more keywords
Pharmacodynamic study of the cardiovascular polypill. Is there any interaction among the monocomponents?
Sign Up to like & getrecommendations! Published in 2020 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2019.11.008
Abstract: INTRODUCTION AND OBJECTIVES To compare the pharmacodynamics of the CNIC polypill (atorvastatin 40mg/ramipril 10mg/aspirin 100mg) in terms of low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP), with the corresponding reference products (atorvastatin and ramipril).… read more here.
Keywords: group; ldl; study; cnic polypill ... See more keywords
COST-EFFECTIVENESS OF POLYPILL TREATMENT IN HIGH-RISK HYPERTENSIVE SUBJECTS WITH HYPER-CHOLESTEROLAEMIA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837684.48681.27
Abstract: Objective: Hypertension and hyper-cholesterolaemia is a dangerous combination frequently found in clinical practice. Despite a wide range of medications available for these both conditions, a large proportion of treated patients remain uncontrolled. We aimed to… read more here.
Keywords: cost; high risk; risk hypertensive; treatment ... See more keywords
IMPACT OF THE CARDIOVASCULAR POLYPILL (TRINOMIA) ON CHRONIC KIDNEY DISEASE. PROSPECTIVE REAL-LIFE DATA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000838108.64719.c2
Abstract: Objective: Cardiovascular diseases are the leading cause of mortality and morbidity worldwide. Moreover, chronic kidney disease (CKD) patients exhibit significantly higher incidence and prevalence of cardiovascular events. In this population, used to a high burden… read more here.
Keywords: cardiovascular polypill; real life; disease; chronic kidney ... See more keywords
A protocol for an economic evaluation of a polypill in patients with established or at high risk of cardiovascular disease in a UK NHS setting: RUPEE (NHS) study
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Open"
DOI: 10.1136/bmjopen-2016-013063
Abstract: Introduction The ‘Use of a Multi-drug Pill in Reducing cardiovascular Events’ (UMPIRE) trial was a randomised controlled clinical trial evaluating the impact of a polypill strategy on adherence to indicated medication in a population with… read more here.
Keywords: risk; rupee nhs; evaluation; polypill ... See more keywords
Heart failure with reduced ejection fraction polypill implementation strategy in Sri Lanka: design and protocol of a pilot type I hybrid randomised clinical trial
Sign Up to like & getrecommendations! Published in 2025 at "BMJ Open"
DOI: 10.1136/bmjopen-2025-100952
Abstract: Introduction Guideline-directed medical therapy (GDMT) for patients with heart failure with reduced ejection fraction (HFrEF) reduces morbidity and mortality and remains widely underused. An HFrEF polypill containing all four pillars of GDMT has been proposed… read more here.
Keywords: sri lanka; trial; type hybrid; polypill ... See more keywords
Abstract 4369574: A Polypill Strategy for Lipid Lowering and Anti-Platelet Therapy After Acute Coronary Syndrome: A Pilot Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4369574
Abstract: Background: Medication non-adherence following acute coronary syndrome (ACS) is a critical implementation gap in socioeconomically disadvantaged patients. The SECURE trial demonstrated benefits of polypill therapy in chronic CAD but excluded P2Y12 inhibitors and did not… read more here.
Keywords: acute coronary; coronary syndrome; group; platelet ... See more keywords
Cut stroke in half: Polypill for primary prevention in stroke
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Stroke"
DOI: 10.1177/1747493018761190
Abstract: This review summarizes the potential for polypill therapies for stroke prevention. While a number of studies applying different approaches regarding polypill have been performed, none of them has had a focus on stroke as the… read more here.
Keywords: stroke half; cut stroke; stroke cut; polypill ... See more keywords
Combined use of polypill components in patients with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Preventive Cardiology"
DOI: 10.1177/2047487318789494
Abstract: Objectives A polypill containing aspirin, a statin and blood pressure (BP)-lowering agents has been proposed for the prevention of cardiovascular disease. To increase adherence and reduce the gaps between indicated and used therapy, a polypill… read more here.
Keywords: use; polypill components; polypill; patients t2dm ... See more keywords