Effects of a Polypill, Aspirin, and the Combination of Both on Cognitive and Functional Outcomes: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.5088
Abstract: Importance Vascular risk factors are associated with cognitive decline but studies addressing individual risk factors have not demonstrated an effect of risk factor management on the preservation of cognition. Few trials have examined the effect… read more here.
Keywords: decline; cognitive functional; risk; randomized clinical ... See more keywords
3D Printing of Four-in-One Oral Polypill with Multiple Release Profiles for Personalized Delivery of Caffeine and Vitamin B Analogues.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120360
Abstract: Personalized supplementation has found recent momentum with an estimated global market size of USD 1.6 billion in 2019 and an expected CAGR of 8.5% between 2020 - 2028. Alongside this rising trend, a simple, accurate,… read more here.
Keywords: vitamin analogues; release profiles; polypill; four one ... See more keywords
Real-life effect on the control of risk factors associated with initiation of the cardiovascular polypill created from equipotent drugs.
Sign Up to like & getrecommendations! Published in 2021 at "Revista clinica espanola"
DOI: 10.1016/j.rceng.2021.05.008
Abstract: OBJECTIVE This work aims to analyze the impact of Spain's National Center for Cardiovascular Research (CNIC-Ferrer)'s cardiovascular (CV)-polypill on blood pressure (BP) and low-density lipoprotein cholesterol (cLDL) levels in patients in our healthcare area who… read more here.
Keywords: initiation; cardiovascular polypill; equally potent; polypill ... See more keywords
Pharmacodynamic study of the cardiovascular polypill. Is there any interaction among the monocomponents?
Sign Up to like & getrecommendations! Published in 2020 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2019.11.008
Abstract: INTRODUCTION AND OBJECTIVES To compare the pharmacodynamics of the CNIC polypill (atorvastatin 40mg/ramipril 10mg/aspirin 100mg) in terms of low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP), with the corresponding reference products (atorvastatin and ramipril).… read more here.
Keywords: group; ldl; study; cnic polypill ... See more keywords
COST-EFFECTIVENESS OF POLYPILL TREATMENT IN HIGH-RISK HYPERTENSIVE SUBJECTS WITH HYPER-CHOLESTEROLAEMIA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837684.48681.27
Abstract: Objective: Hypertension and hyper-cholesterolaemia is a dangerous combination frequently found in clinical practice. Despite a wide range of medications available for these both conditions, a large proportion of treated patients remain uncontrolled. We aimed to… read more here.
Keywords: cost; high risk; risk hypertensive; treatment ... See more keywords
IMPACT OF THE CARDIOVASCULAR POLYPILL (TRINOMIA) ON CHRONIC KIDNEY DISEASE. PROSPECTIVE REAL-LIFE DATA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000838108.64719.c2
Abstract: Objective: Cardiovascular diseases are the leading cause of mortality and morbidity worldwide. Moreover, chronic kidney disease (CKD) patients exhibit significantly higher incidence and prevalence of cardiovascular events. In this population, used to a high burden… read more here.
Keywords: cardiovascular polypill; real life; disease; chronic kidney ... See more keywords
A protocol for an economic evaluation of a polypill in patients with established or at high risk of cardiovascular disease in a UK NHS setting: RUPEE (NHS) study
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Open"
DOI: 10.1136/bmjopen-2016-013063
Abstract: Introduction The ‘Use of a Multi-drug Pill in Reducing cardiovascular Events’ (UMPIRE) trial was a randomised controlled clinical trial evaluating the impact of a polypill strategy on adherence to indicated medication in a population with… read more here.
Keywords: risk; rupee nhs; evaluation; polypill ... See more keywords
Cut stroke in half: Polypill for primary prevention in stroke
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Stroke"
DOI: 10.1177/1747493018761190
Abstract: This review summarizes the potential for polypill therapies for stroke prevention. While a number of studies applying different approaches regarding polypill have been performed, none of them has had a focus on stroke as the… read more here.
Keywords: stroke half; cut stroke; stroke cut; polypill ... See more keywords
Combined use of polypill components in patients with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Preventive Cardiology"
DOI: 10.1177/2047487318789494
Abstract: Objectives A polypill containing aspirin, a statin and blood pressure (BP)-lowering agents has been proposed for the prevention of cardiovascular disease. To increase adherence and reduce the gaps between indicated and used therapy, a polypill… read more here.
Keywords: use; polypill components; polypill; patients t2dm ... See more keywords
Cost-effectiveness analysis of use of a polypill versus usual care or best practice for primary prevention in people at high risk of cardiovascular disease
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182625
Abstract: Background Clinical trials suggest that use of fixed-dose combination therapy (‘polypills’) can improve adherence to medication and control of risk factors of people at high risk of cardiovascular disease (CVD) compared to usual care, but… read more here.
Keywords: risk; cost effective; usual care; polypill ... See more keywords
Practical Decision Algorithms for the Use of the Cardiovascular Polypill in Secondary Prevention in Europe
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.663361
Abstract: The main objective of cardiovascular disease (CVD) prevention is to reduce morbidity and mortality. Despite recommendations on evidence-based pharmacological treatment and lifestyle changes, the control of CV risk factors such as hypertension or dyslipidaemia is… read more here.
Keywords: use; treatment; secondary prevention; risk factors ... See more keywords