CHRONOCRISIS: When Cell Cycle Asynchrony Generates DNA Damage in Polyploid Cells
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DOI: 10.1002/bies.202000105
Abstract: Polyploid cells contain multiple copies of all chromosomes. Polyploidization can be developmentally programmed to sustain tissue barrier function or to increase metabolic potential and cell size. Programmed polyploidy is normally associated with terminal differentiation and… read more here.
Keywords: polyploid; dna damage; cell cycle; polyploid cells ... See more keywords
FC 041TUBULAR EPITHELIAL CELL POLYPLOIDY IS ESSENTIAL TO SURVIVE AKI BUT IT CONTRIBUTES TO CKD PROGRESSION
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab119.001
Abstract: Acute Kidney Injury (AKI) is a syndrome characterized by an acute deterioration of renal function. Due to its high prevalence and poor short-term outcomes, AKI represents a global healthcare issue. Many epidemiologic studies have indicated… read more here.
Keywords: ckd progression; cell; polyploid cells; kidney ... See more keywords