A report of intraspecific polyploidy (4x, 6x) in Festuca gigantea (L.) Vill (Family: Poaceae) from Western Himalaya, India and comments on its cyto-geography
Sign Up to like & getrecommendations! Published in 2021 at "Nucleus"
DOI: 10.1007/s13237-020-00347-8
Abstract: Two cytotypes of ‘giant fescue’ sporting gametic chromosome number of n = 14 and n = 21 corresponding to 4x and 6x ploidy level (based on x = 7) were encountered in the various localities in India falling in the Western… read more here.
Keywords: polyploidy festuca; geography; intraspecific polyploidy; report intraspecific ... See more keywords
The Polyploid State Plays a Tumor-Suppressive Role in the Liver.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.01.010
Abstract: Most cells in the liver are polyploid, but the functional role of polyploidy is unknown. Polyploidization occurs through cytokinesis failure and endoreduplication around the time of weaning. To interrogate polyploidy while avoiding irreversible manipulations of essential… read more here.
Keywords: polyploid state; role; state plays; liver polyploid ... See more keywords
Targeting tumor cell senescence and polyploidy as potential therapeutic strategies.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2020.12.010
Abstract: Senescence is a unique state of growth arrest that develops in response to a plethora of cellular stresses, including replicative exhaustion, oxidative injury, and genotoxic insults. Senescence has been implicated in the pathogenesis of multiple… read more here.
Keywords: senescence; tumor cells; therapeutic strategies; cancer ... See more keywords
Polyploidy and the mitosis path to epidermal cell fate
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DOI: 10.1080/15384101.2019.1568766
Abstract: The cell cycle mechanisms coordinating proliferation with differentiation in epidermis remain intriguing and somewhat controversial. For decades it was assumed that differentiating keratinocytes underwent growth and cell cycle arrest in G0. This concept was supported… read more here.
Keywords: mitosis; differentiating keratinocytes; differentiation; cell fate ... See more keywords
The direct effects of plant polyploidy on the legume–rhizobia mutualism
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Botany"
DOI: 10.1093/aob/mcx121
Abstract: Background Polyploidy is known to significantly alter plant genomes, phenotypes and interactions with the abiotic environment, yet the impacts of polyploidy on plant-biotic interactions are less well known. A particularly important plant-biotic interaction is the… read more here.
Keywords: plant; legume rhizobia; rhizobia mutualism; plant polyploidy ... See more keywords
False positivity in break apart fluorescence in-situ hybridization due to polyploidy
Sign Up to like & getrecommendations! Published in 2023 at "Translational Lung Cancer Research"
DOI: 10.21037/tlcr-22-516
Abstract: Background In-situ hybridization (ISH) is a diagnostic tool in the detection of chromosomal anomalies, which has important implications for diagnosis, classification and prediction of cancer therapy in various diseases. Certain thresholds of number of cells… read more here.
Keywords: lung cancer; situ hybridization; polyploidy; break apart ... See more keywords
Impact of polyploidy on plant tolerance to abiotic and biotic stresses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.869423
Abstract: Polyploidy, defined as the coexistence of three or more complete sets of chromosomes in an organism’s cells, is considered as a pivotal moving force in the evolutionary history of vascular plants and has played a… read more here.
Keywords: abiotic biotic; polyploidy; biotic stresses; plant ... See more keywords
Polyploidy as an Adaptation against Loss of Heterozygosity in Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158528
Abstract: Polyploidy is common in cancer cells and has implications for tumor progression and resistance to therapies, but it is unclear whether it is an adaptation of the tumor or the non-adaptive effect of genomic instability.… read more here.
Keywords: loss heterozygosity; adaptation; loss; polyploidy ... See more keywords
Cytogenetics and Consequences of Polyploidization on Different Biotic-Abiotic Stress Tolerance and the Potential Mechanisms Involved
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DOI: 10.3390/plants11202684
Abstract: The application of polyploidy in sustainable agriculture has already brought much appreciation among researchers. Polyploidy may occur naturally or can be induced in the laboratory using chemical or gaseous agents and results in complete chromosome… read more here.
Keywords: stress; polyploidization different; polyploidy; consequences polyploidization ... See more keywords