homo-Adamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum hookerianum.
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DOI: 10.1016/j.fitote.2018.12.014
Abstract: Hookeriones I-Q (1-9), nine new homo-adamantane type polycyclic polyprenylated acylphloroglucinols (PPAPs), were isolated from Hypericum hookerianum, along with twenty known analogues. These structures were determined on the basis of comprehensive NMR and MS spectroscopic data.… read more here.
Keywords: adamantane type; type polycyclic; homo adamantane; hypericum hookerianum ... See more keywords
Hyperacmosins E-G, three new homoadamantane-type polyprenylated acylphloroglucinols from Hypericum acmosepalum.
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DOI: 10.1016/j.fitote.2020.104535
Abstract: Three new homoadamantane-type polyprenylated acylphloroglucinols, hyperacmosins E-G (1-3), with seven known compounds were isolated from the air-dried aerial parts of Hypericum asmosepalum. Their structures were determined by NMR, HRESIMS and experimental electronic circular dichroism (ECD)… read more here.
Keywords: type polyprenylated; homoadamantane type; new homoadamantane; three new ... See more keywords
Discovery of Undescribed Monoterpenoid Polyprenylated Acylphloroglucinols with Immunosuppressive Activities from Hypericum longistylum.
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DOI: 10.1016/j.phytochem.2022.113173
Abstract: Acylphlorostylums A-G (1-7), seven undescribed monoterpenoid polyprenylated acylphloroglucinols, were isolated and identified from Hypericum longistylum. Significantly, acylphlorostylums A and B were the first monoterpenoid polyprenylated acylphloroglucinols possessing a dodecahydro-1H-benzo [b]cyclopenta [e]oxepine moiety bearing a notable… read more here.
Keywords: monoterpenoid polyprenylated; discovery undescribed; polyprenylated acylphloroglucinols; hypericum longistylum ... See more keywords
Four intricately caged polycyclic polyprenylated acylphloroglucinols from Garcinia multiflora fruits
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DOI: 10.1039/c9qo00586b
Abstract: Garmultinones A–C (1–3), three polycyclic polyprenylated acylphloroglucinols (PPAPs) with a unique caged tricyclo[3.3.1.1.4,8]decane skeleton, and one PPAP garmultinone D (4) with the tricyclo[4.3.1.03,7]decane skeleton bearing the 2,2-dimethyl-3-isopropenylcyclopentyl ring were isolated from the fruits of Garcinia… read more here.
Keywords: polyprenylated acylphloroglucinols; garcinia multiflora; caged polycyclic; four intricately ... See more keywords
Discovery of new polycyclic polyprenylated acylphloroglucinols with diverse architectures as potent cyclooxygenase-2 inhibitors
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DOI: 10.1039/d0qo00259c
Abstract: Cyclooxygenase-2 (COX-2) is a significant therapeutic target of chronic inflammatory diseases. Soniiglucinols A–D (1–4), four new polycyclic polyprenylated acylphloroglucinols (PPAPs) with diverse architectures, were isolated from Hypericum wilsonii. Structurally, 1 and 2 represent the first… read more here.
Keywords: cyclooxygenase; diverse architectures; potent cyclooxygenase; new polycyclic ... See more keywords
Discovery of bicyclic polyprenylated acylphloroglucinols from Hypericum himalaicum with glucose transporter 4 translocation activity.
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DOI: 10.2139/ssrn.4187001
Abstract: Hyperhimatins A-P (1-16), sixteen new bicyclic polyprenylated acylphloroglucinols (BPAPs), were isolated and identified from Hypericum himalaicum. The planner structures of hyperhimatins A-P were confirmed via extensive NMR and careful HRESIMS data analysis. The absolute configurations… read more here.
Keywords: bicyclic polyprenylated; hypericum himalaicum; translocation; glucose transporter ... See more keywords