SWI/SNF Dysregulation through a Prion-like Domain Causes AML
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DOI: 10.1182/blood-2019-129280
Abstract: Meningioma-1 (MN1) was first described in a sporadic t(4;22) translocation in meningioma. Rare MN1 fusions to the ETS factors ETV6 (t(12;22)) and FLI1 (cryptic) also occur in AML. t(12;22) translocations have been described in two… read more here.
Keywords: protein; mn1; prion like; polyq stretch ... See more keywords