Self-reactive and polyreactive B cells are generated and selected in the germinal center during γ-herpesvirus infection.
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DOI: 10.1093/intimm/dxz057
Abstract: Immune responses against certain viruses are accompanied by autoantibody production although the origin of these infection-associated autoantibodies is unclear. Here we report that murine γ-herpesvirus 68 (MHV68)-induced autoantibodies are derived from polyreactive B cells in… read more here.
Keywords: polyreactive cells; germinal center; cells generated; infection ... See more keywords