Polysialic acid-mediated activity measurement of polysialylated recombinant coagulation factor VIII.
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DOI: 10.1016/j.xphs.2019.10.019
Abstract: Measurement of modified biologic including coagulation factors with extended half-life obtained for example by polysialylation pose an analytical challenge especially if both biological activity and presence of modification have to be determined. Analytical methods applied… read more here.
Keywords: polysialic acid; acid mediated; factor viii; polysialylated recombinant ... See more keywords