The Use of Surfactants to Solubilise a Glucagon Analogue
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2494-2
Abstract: ABSTRACTPurposeThe peptide hormone glucagon, used to treat hypoglycaemic incidents, is prone to aggregation. Generating alternatives with better stability is of pharmaceutical interest in the treatment of diabetes. Here we investigate the impact of six different… read more here.
Keywords: use surfactants; glucagon; polysorbate; use ... See more keywords
Characteristics and antitumor activity of polysorbate 80 curcumin micelles preparation by cloud point cooling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101871
Abstract: Abstract Curcumin is a natural bioactive compound with known potential for cancer treatment and prevention. However, a major barrier for clinical application is its poor solubility and bioavailability. Nanotechnology is an effective approach to enhance… read more here.
Keywords: polysorbate; antitumor activity; characteristics antitumor; cloud point ... See more keywords
Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.08.011
Abstract: We examined how polysorbate 20 (PS20; Tween 20) and polysorbate 80 (PS80; Tween 80) affect the higher-order structure of a monoclonal antibody (mAb) and its antigen-binding (Fab) and crystallizable (Fc) fragments, using near-UV circular dichroism… read more here.
Keywords: polysorbate; structure monoclonal; higher order; spectroscopy ... See more keywords
Polysorbate 80 blocked a peripheral sodium channel, Nav1.7, and reduced neuronal excitability
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pain"
DOI: 10.1177/17448069221150138
Abstract: Polysorbate 80 is a non-ionic detergent derived from polyethoxylated sorbitan and oleic acid. It is widely used in pharmaceuticals, foods, and cosmetics as an emulsifier. Nav1.7 is a peripheral sodium channel that is highly expressed… read more here.
Keywords: state; sodium channel; peripheral sodium; polysorbate ... See more keywords
Enhancement of Enzymatic Hydrolysis of Sugarcane Bagasse by the Combination of Delignification Pretreatment and Polysorbate 80
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DOI: 10.3390/fermentation9040371
Abstract: Delignification pretreatment with alkali under various conditions (25–160 °C for 1–12 h) or sodium chlorite at 75 °C for 4 h was applied to improve the enzymatic digestibility of sugarcane bagasse by removing hemicellulose and… read more here.
Keywords: delignification; hydrolysis; sugarcane bagasse; polysorbate ... See more keywords
Antimicrobial Activity of Polysorbate 80-iodine Complex: Polysorbate 80 Firmly Retains Iodine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of oleo science"
DOI: 10.5650/jos.ess22115
Abstract: Considering that iodine is highly volatile and has low solubility in water, it is utilized as an antiseptic in its complex form (iodophor) with a carrier material. Herein, we prepared the polysorbate 80-iodine complex and… read more here.
Keywords: iodine complex; polysorbate firmly; iodine; activity ... See more keywords