Stable, Bioresponsive, and Macrophage-Evading Polyurethane Micelles Containing an Anionic Tripeptide Chain Extender
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b02326
Abstract: Polymeric nanocarriers have been extensively used in medicinal applications for drug delivery. However, intravenous nanocarriers circulating in the blood will be rapidly cleared from the mononuclear macrophage system. The surface physicochemical characterizations of nanocarriers are… read more here.
Keywords: micelles containing; stable bioresponsive; anionic tripeptide; polyurethane micelles ... See more keywords
Effect of the disulfide bond and polyethylene glycol on the degradation and biophysicochemical properties of polyurethane micelles.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm01422f
Abstract: The disulfide bond has emerged as a promising redox-sensitive switch for smart polymeric micelles, due to its properties of rapid response to the reductive environment and spatiotemporally-controlled therapeutic agent delivery. However, the dilemma of multifunctional… read more here.
Keywords: polyurethane micelles; polyethylene glycol; degradation; disulfide bond ... See more keywords