Association between serum paraoxonase 1 activity and its polymorphisms with multiple sclerosis: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04842-3
Abstract: Human serum paraoxonase (PON) is an enzyme that is synthesized by the liver and enters the bloodstream, and it is transmitted by high-density lipoproteins (HDL). Paraoxonase 1 (PON1) is a hydrolytic enzyme with a wide… read more here.
Keywords: sclerosis; serum paraoxonase; pon1; multiple sclerosis ... See more keywords
Epistasis between ADIPOQ rs1501299 and PON1 rs662 polymorphisms is potentially associated with the development of knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04654-5
Abstract: Overweight produces oxidative stress (OS) on the articular cartilage, with the subsequent risk of developing knee osteoarthritis (OA). Associations between genetic polymorphisms related to OS and OA have been reported, but it is currently unknown… read more here.
Keywords: rs1501299; pon1; epistasis; knee ... See more keywords
Serum Amyloid A, Paraoxonase-1 Activity, and Apolipoprotein Concentrations as Biomarkers of Subclinical Atherosclerosis Risk in Adrenal Incidentaloma Patients.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2018.07.002
Abstract: BACKGROUND Adrenal incidentalomas (AIs), particularly subclinical hypercortisolism (SH), are related to an increased risk of atherosclerosis. The anti-oxidative enzyme paraoxonase-1 (PON1) and the acute phase reactant serum amyloid A (SAA) are transported by highdensity lipoprotein… read more here.
Keywords: saa pon1; serum amyloid; subclinical atherosclerosis; pon1 ... See more keywords
The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.07.010
Abstract: BACKGROUND Paraoxonase 1 (PON1) is an important antiatherogenic and antioxidant enzyme in the circulation that has been associated with adverse health outcomes particularly cardiovascular disease (CVD) and other metabolic disorders. PON1 is a highly promiscuous… read more here.
Keywords: enzyme; pon1; paraoxonase pon1; pon1 important ... See more keywords
Effects of nanoparticles exposure and PON1 genotype on heart rate variability.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental research"
DOI: 10.1016/j.envres.2019.03.015
Abstract: OBJECTIVES This study was to assess the association between different NPs exposure and PON1 genotype on Heart Rate Variability (HRV) parameters among workers. METHODS This study included 235 non-CVD subjects handled to nanomaterials (NM) and… read more here.
Keywords: exposure pon1; heart rate; genotype heart; exposure ... See more keywords
PON1 status and homocysteine levels as potential biomarkers for cardiovascular disease
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.111062
Abstract: BACKGROUND Cardiovascular disease (CVD) is the leading cause of death. The mainly risks factors for CVD are diabetes, hypertension and high levels of homocysteine (Hcys), among others. Paraoxonase 1 (PON1) has been proposed as an… read more here.
Keywords: pon1; cardiovascular disease; hcys; pon1 concentration ... See more keywords
Assessment of PPARGC1A, PPARGC1B, and PON1 Genetic Polymorphisms in Esophageal Squamous Cell Carcinoma Susceptibility in the Eastern Chinese Han Population: A Case-Control Study Involving 2351 Subjects.
Sign Up to like & getrecommendations! Published in 2020 at "DNA and cell biology"
DOI: 10.1089/dna.2020.5416
Abstract: Previous studies suggested that alterations in the energy metabolism might be underlying cancer initiation and progression. Polymorphisms of genes involved in energy metabolism regulation, such as peroxisome proliferator-activated receptor gamma coactivator 1α (PPARGC1A), -β (PPARGC1B),… read more here.
Keywords: pon1; cell; ppargc1a ppargc1b; susceptibility ... See more keywords
Relationship Between Paraoxonase-1 and Butyrylcholinesterase Activities and Nutritional Status in Mexican Children.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2017.0138
Abstract: BACKGROUND The enzymes butyrylcholinesterase (BuChE) and paraoxonase-1 (PON1) are the primary bioscavenging enzymes in serum and exhibit antioxidant and anti-inflammatory activities. PON1 has been associated with diseases caused by high oxidative stress, whereas BuChE appears… read more here.
Keywords: pon1 l55m; buche; pon1; nutritional status ... See more keywords
Paraoxonase 1 and atrial fibrillation: Is there a relationship?
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031553
Abstract: Atrial fibrillation (AF) is associated with oxidative stress and inflammation. Paraoxonase-1 (PON1), circulates in blood bound to high-density lipoproteins and reduces systemic oxidative stress. The aim of this study was to evaluate PON1 serum concentration… read more here.
Keywords: pon1; pon1 concentration; atrial fibrillation; arease ... See more keywords
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental biology and medicine"
DOI: 10.1177/15353702221128563
Abstract: In this study, we aimed to investigate the effect of paraoxonase 1 (PON1) rs662 polymorphism, arylesterase (ARE) activity, and the serum lipid profile in patients with coronavirus disease 2019 (COVID-19) in different stages of the… read more here.
Keywords: polymorphism; post covid; rs662 polymorphism; activity ... See more keywords
Impact of the 24-h ultramarathon race on homocysteine, oxidized low-density lipoprotein, and paraoxonase 1 levels in professional runners
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0192392
Abstract: The impact of the 24-h ultramarathon race on homocysteine (Hcy) and oxidized low-density lipoprotein (oxLDL) levels, two well-recognized cardiovascular risk factors, has not been deeply investigated. Similarly, no information exists on paraoxonase 1 (PON1), an… read more here.
Keywords: ultramarathon race; density; pon1; race homocysteine ... See more keywords