Insights into the role of paraoxonase 2 in human pathophysiology
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biosciences"
DOI: 10.1007/s12038-021-00234-7
Abstract: Paraoxonase 2 (PON2) is a ubiquitously expressed intracellular enzyme that is known to have a protective role from oxidative stress. Clinical studies have also demonstrated the significance of PON2 in the manifestation of cardiovascular and… read more here.
Keywords: pon2; insights role; role paraoxonase; oxidative stress ... See more keywords
Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.02.008
Abstract: OBJECTIVE To investigate the novel role of Paraoxonase 2 (PON2) in modulating acute myocardial ischemia-reperfusion injury (IRI). APPROACH IRI was induced both in vivo and ex vivo in male, C57BL6/J (WT) and PON2-deficient (PON-def) mice.… read more here.
Keywords: pi3k; h9c2; mice; acute myocardial ... See more keywords
Global P2P BitTorrent Real-Time Traffic Over SDN-Based Local-Aware NG-PON2
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3192439
Abstract: File sharing is one of the most common uses in Peer-to-peer (P2P) networks and structured P2P systems, such as BitTorrent (BT), which may overcome the limitations of features such as improved scalability, efficiency, and deterministic… read more here.
Keywords: p2p; pon2; traffic; real time ... See more keywords
CircHIPK3 prevents chondrocyte apoptosis and cartilage degradation by sponging miR‐30a‐3p and promoting PON2
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13285
Abstract: Osteoarthritis (OA) is a common joint disease featured by the deterioration of articular cartilage and chondrocyte death. Emerging evidence has indicated that circular RNAs (circRNAs) play an essential role in OA progress. Here, we found… read more here.
Keywords: apoptosis; chondrocyte apoptosis; circhipk3; cartilage ... See more keywords
Airway epithelial Paraoxonase-2 in obese asthma
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DOI: 10.1371/journal.pone.0261504
Abstract: Background Obesity in asthmatics has been associated with higher airway oxidative stress in which dysfunctional mitochondria are a potential contributing source of excess free radicals. Paraoxonase 2 (PON2) plays an important role in reducing mitochondrial-derived… read more here.
Keywords: stress; airway epithelial; quercetin supplementation; oxidative stress ... See more keywords