Genome-scale CRISPR pooled screens.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2016.05.014
Abstract: Genome editing technologies such as clustered regularly interspaced short palindromic repeats (CRISPR) systems have ushered in a new era of targeted DNA manipulation. The easy programmability of CRISPR using short oligonucleotides enables rapid synthesis of… read more here.
Keywords: biochemistry; genome scale; crispr; pooled screens ... See more keywords
Abstract LB042: An automated workflow for optical pooled screens with massively multiplexed phenotypic readouts on AVITI24
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-lb042
Abstract: Optical pooled screening (OPS) is a powerful tool for linking image-based measurements of cellular phenotypes with in situ readouts of genetic perturbations, and has been used to identify the regulators of diverse biological processes, such… read more here.
Keywords: automated workflow; workflow optical; pooled screens; screens massively ... See more keywords