Poor graft function after allogeneic hematopoietic stem cell transplantation-an old complication with new insights☆.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2018.08.004
Abstract: Poor graft function (PGF), characterized by pancytopenia, is a life-threatening complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT). PGF has become a growing obstacle that contributes to high morbidity and mortality after allo-HSCT, especially with… read more here.
Keywords: graft function; pgf; poor graft; hematopoietic stem ... See more keywords
Use of eltrombopag for the treatment of poor graft function after hematopoietic stem cell transplantation in children
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DOI: 10.1111/petr.14010
Abstract: The main objective of this study was to determine whether Eltrombopag, a synthetic thrombopoietin receptor agonist, could improve peripheral blood counts in the three hematopoietic lineages and achieve transfusion independence in children with poor graft… read more here.
Keywords: graft function; treatment; poor graft; stem cell ... See more keywords
Advances in the understanding of poor graft function following allogeneic hematopoietic stem-cell transplantation
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DOI: 10.1177/2040620720948743
Abstract: Poor graft function (PGF) following allogeneic hematopoietic stem-cell transplantation (allo-HSCT) is a life-threatening complication and is characterized by bilineage or trilineage blood cell deficiency and hypoplastic marrow with full chimerism. With the rapid development of… read more here.
Keywords: pgf; poor graft; stem cell; stem ... See more keywords
Eltrombopag for Post-Transplant Poor Graft Function in East Asian Patients
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DOI: 10.3346/jkms.2022.37.e48
Abstract: Poor graft function (PGF) is a serious, potentially life-threatening complication of allogeneic hematopoietic stem cell transplantation. Eltrombopag has shown multilineage responses in patients with refractory severe aplastic anemia, supporting the idea that it may improve… read more here.
Keywords: eltrombopag post; transplant; graft function; poor graft ... See more keywords
Recent Advancements in Poor Graft Function Following Hematopoietic Stem Cell Transplantation
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DOI: 10.3389/fimmu.2022.911174
Abstract: Poor graft function (PGF) is a life-threatening complication that occurs after transplantation and has a poor prognosis. With the rapid development of haploidentical hematopoietic stem cell transplantation, the pathogenesis of PGF has become an important… read more here.
Keywords: stem cell; graft function; transplantation; poor graft ... See more keywords
Eltrombopag for the Treatment of Poor Graft Function Following Haematopoietic Cell Transplantation: Real-Life Data
Sign Up to like & getrecommendations! Published in 2022 at "Balkan Medical Journal"
DOI: 10.4274/balkanmedj.galenos.2022.2022-2-48
Abstract: Background: Eltrombopag has an off-label indication for haematopoietic cell transplantation in patients experiencing delayed thrombocyte recovery and/or thrombocytopaenia. Aims: To present our centre’s experience of using this agent not only for post- haematopoietic cell transplantation… read more here.
Keywords: haematopoietic cell; treatment; poor graft; cell transplantation ... See more keywords