Targeted O‐glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced‐stage bladder tumours
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12035
Abstract: Bladder carcinogenesis and tumour progression is accompanied by profound alterations in protein glycosylation on the cell surface, which may be explored for improving disease management. In a search for prognosis biomarkers and novel therapeutic targets… read more here.
Keywords: poor prognosis; bladder; bladder tumours; advanced stage ... See more keywords
Overexpression of GLT1D1 induces immunosuppression through glycosylation of PD‐L1 and predicts poor prognosis in B‐cell lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12664
Abstract: B‐cell non‐Hodgkin's lymphoma (NHL) is a class of heterogeneous diseases with variable clinical outcomes. Immunosuppression is particularly common in the subtypes of lymphoma with poor prognosis, but the underlying mechanism remains unclear. Using a RT‐PCR… read more here.
Keywords: poor prognosis; glt1d1; overexpression glt1d1; cell ... See more keywords
eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4848
Abstract: Colorectal cancer (CRC) is a major leading cause of cancer mortality worldwide in which dysregulated protein synthesis plays an etiologic role. The eukaryotic elongation factor 1 A1 (eEF1A1) exerts significant effects on protein synthesis by… read more here.
Keywords: eef1a1; poor prognosis; crc; colorectal cancer ... See more keywords
MAPK4 predicts poor prognosis and facilitates the proliferation and migration of glioma through the AKT/mTOR pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5859
Abstract: Mitogen‐activated protein kinase 4 (MAPK4) is an atypical member of the mitogen‐activated protein kinase (MAPK) family. We report here that MAPK4 is overexpressed in glioma. The clinical significance, biological roles and underlying molecular mechanisms through… read more here.
Keywords: facilitates proliferation; mapk4 predicts; predicts poor; poor prognosis ... See more keywords
Low T3 syndrome as a predictor of poor prognosis in chronic lymphocytic leukemia
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DOI: 10.1002/ijc.31327
Abstract: Low triiodothyronine (T3) state is associated with poor prognosis in critical acute and prolonged illness. However, the information on thyroid dysfunction and cancer is limited. The aim of our study was to evaluate the prognostic… read more here.
Keywords: low syndrome; lymphocytic leukemia; poor prognosis; chronic lymphocytic ... See more keywords
MicroRNA‐124‐3p.1 promotes cell proliferation through Axin1‐dependent Wnt signaling pathway and predicts a poor prognosis of triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23266
Abstract: Triple‐negative breast cancer (TNBC) is one subtype of breast cancer, which is characterized by an aggressive disease. It is commonly accompanied with extremely poor prognosis because of no available molecularly targeted therapy. Thus, understanding the… read more here.
Keywords: negative breast; poor prognosis; breast; breast cancer ... See more keywords
Serum amyloid A‐to‐albumin ratio as a potential biomarker to predict the activity, severity, and poor prognosis of systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24282
Abstract: To evaluate the predictive value of serum amyloid A‐to‐albumin ratio (SAR) for active systemic lupus erythematosus (SLE), severe active SLE, and poor prognosis of SLE. read more here.
Keywords: lupus erythematosus; serum amyloid; poor prognosis; systemic lupus ... See more keywords
The predictive value of fibrinogen‐to‐albumin ratio in the active, severe active, and poor prognosis of systemic lupus erythematosus: A single‐center retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24621
Abstract: To evaluate the prediction and effect of fibrinogen‐to‐albumin ratio (FAR) on active, severe active, and poor prognosis of systemic lupus erythematosus (SLE). read more here.
Keywords: poor prognosis; severe active; fibrinogen albumin; albumin ratio ... See more keywords
PPP3CB contributes to poor prognosis through activating nuclear factor of activated T‐cells signaling in neuroblastoma
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DOI: 10.1002/mc.22939
Abstract: We previously identified a gain‐of‐function mutation in PPP3CB in a neuroblastoma (NB) with MYCN amplification. Here we investigated the functional and clinical role of PPP3CB in NB. High PPP3CB expression was an independent indicator predicting… read more here.
Keywords: ppp3cb; poor prognosis; expression; cell ... See more keywords
Fungation in soft tissue sarcomas is associated with poor survival
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DOI: 10.1007/s00264-017-3628-6
Abstract: PurposeWhilst much is known on the multiple variables associated with a poor prognosis in soft tissue sarcomas, little evidence exists on the impact of fungation at the time of presentation. The aim of this study… read more here.
Keywords: poor prognosis; soft tissue; associated poor; tissue sarcomas ... See more keywords
Phosphorylation of EphA2 receptor and vasculogenic mimicry is an indicator of poor prognosis in invasive carcinoma of the breast
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05482-8
Abstract: Purpose The occurrence of vasculogenic mimicry (VM) and EphA2-mediated tumour progression are associated with poor prognosis in various solid tumours. Here, we aimed to investigate the prognostic implications of VM and its association with phosphorylated… read more here.
Keywords: phospho epha2; epha2 s897; poor prognosis; breast ... See more keywords