Articles with "poor prognostic" as a keyword



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Poor prognostic factors in predicting abatacept response in a phase III randomized controlled trial in psoriatic arthritis

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Published in 2020 at "Rheumatology International"

DOI: 10.1007/s00296-020-04564-x

Abstract: In ASTRAEA (NCT01860976), abatacept significantly increased American College of Rheumatology criteria 20% (ACR20) responses at Week 24 versus placebo in patients with psoriatic arthritis (PsA). This post hoc analysis explored relationships between prospectively identified baseline… read more here.

Keywords: psoriatic arthritis; response; poor prognostic; rheumatology ... See more keywords
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Is the presence of antiphospholipid antibodies a poor prognostic factor for patients with HELLP syndrome?

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Published in 2021 at "American journal of obstetrics and gynecology"

DOI: 10.1016/j.ajog.2021.03.039

Abstract: BACKGROUND The characteristics of antiphospholipid syndrome (APS)-associated HELLP syndrome are poorly described, likely due to the low frequency of this combination of syndromes. OBJECTIVE To compare the characteristics and prognosis of HELLP syndrome in patients… read more here.

Keywords: hellp syndrome; aps patients; hellp aps; poor prognostic ... See more keywords
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Expanding the Criteria for Nipple‐Sparing Mastectomy in Patients With Poor Prognostic Features

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Published in 2018 at "Clinical Breast Cancer"

DOI: 10.1016/j.clbc.2017.08.010

Abstract: Micro‐Abstract In many institutions, nipple‐sparing mastectomy (NSM) is reserved for prophylaxis or for early‐stage breast cancer. With increasing utility of neoadjuvant chemotherapy (NAC), patients with poor prognostic features may downstage significantly. In this retrospective review… read more here.

Keywords: breast; poor prognostic; sparing mastectomy; nipple sparing ... See more keywords
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Tumor necrosis in radical prostatectomies with high-grade prostate cancer is associated with multiple poor prognostic features and a high prevalence of residual disease.

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Published in 2018 at "Human pathology"

DOI: 10.1016/j.humpath.2017.11.015

Abstract: The Gleason grading system and the recently defined Grade Groups are strong, well-established predictors of outcome in prostate cancer. Each Gleason score, however, is the result of a sum of categories (Gleason patterns or GPs)… read more here.

Keywords: poor prognostic; prostate cancer; features high; tumor necrosis ... See more keywords
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A new bioinformatics approach identifies overexpression of GRB2 as a poor prognostic biomarker for prostate cancer

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-85086-9

Abstract: A subset of prostate cancer displays a poor clinical outcome. Therefore, identifying this poor prognostic subset within clinically aggressive groups (defined as a Gleason score (GS) ≧8) and developing effective treatments are essential if we… read more here.

Keywords: prostate; poor prognostic; prostate cancer; shorter survival ... See more keywords
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Intratympanic steroid therapy for Bell’s palsy with poor prognostic results

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-87551-x

Abstract: In Bell’s palsy, electrodiagnosis by electroneurography (ENoG) is widely used to predict a patient’s prognosis. The therapeutic options for patients with poor prognostic results remain controversial. Here, we investigated whether early intervention with intratympanic steroid… read more here.

Keywords: bell palsy; poor prognostic; prognostic results; bell ... See more keywords
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PS02.070: DEEP NEURAL NETWORK TO PREDICT POOR PROGNOSTIC FACTORS IN PATIENTS WITH ESOPHAGEAL CANCER

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Published in 2018 at "Diseases of the Esophagus"

DOI: 10.1093/dote/doy089.ps02.070

Abstract: Both lymphovascular invasion, which is characterized by penetration of tumor cells into the peritumoural vascular or lymphatic network, and perineural invasion, which is characterized by involvement of tumor cells surrounding nerve fibers, are considered as… read more here.

Keywords: esophageal cancer; network; invasion; poor prognostic ... See more keywords
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Abstract P3-08-01: MONARCH 2: Interim analysis of overall survival in patients with poor prognostic factors

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs19-p3-08-01

Abstract: Background: In MONARCH 2 (M2), abemaciclib, an oral selective cyclin dependent kinase 4 & 6 inhibitor, demonstrated significant progression-free survival (PFS) improvement in hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-)… read more here.

Keywords: prognostic factors; poor prognostic; breast cancer; cancer ... See more keywords
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HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer

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Published in 2021 at "BMC Medical Genomics"

DOI: 10.1186/s12920-021-01043-5

Abstract: Background SMARCAs, belonged to SWI/SNF2 subfamilies, are critical to cellular processes due to their modulation of chromatin remodeling processes. Although SMARCAs are implicated in the tumor progression of various cancer types, our understanding of how… read more here.

Keywords: poor prognostic; pancreatic cancer; hells serves; cancer ... See more keywords
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Benefit From Fractionated Dose-Dense Chemotherapy in Patients With Poor Prognostic Ovarian Cancer: ICON-8 Trial.

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Published in 2023 at "JCO clinical cancer informatics"

DOI: 10.1200/cci.22.00188

Abstract: PURPOSE An international meta-analysis identified a group of patients with advanced epithelial ovarian cancer (EOC) with a very poor survival because of two unfavorable features: (1) a poor chemosensitivity defined by an unfavorable modeled CA-125… read more here.

Keywords: surgery; dense chemotherapy; poor prognostic; dose dense ... See more keywords
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Modulation of plasma lipidomic signature in metastatic castration-resistant prostate cancer (mCRPC).

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.7_suppl.tps331

Abstract: TPS331 Background: Altered lipid metabolism and its impact on prostate cancer (PC) is increasingly recognised, in light of the association between obesity and worse PC outcomes. Our exploratory study was the first to identify baseline… read more here.

Keywords: mcrpc; signature; prostate cancer; poor prognostic ... See more keywords