Articles with "poor survival" as a keyword



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ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells

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Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.2965

Abstract: Alanine‐serine‐cysteine transporter 2 (ASCT2), a major glutamine transporter, is essential for cell growth and tumor development in a variety of cancers. However, the clinicopathological significance and pathological role of ASCT2 in OSCC (oral squamous cell… read more here.

Keywords: associated poor; poor survival; asct2 overexpression; growth ... See more keywords

Enolase1 overexpression regulates the growth of gastric cancer cells and predicts poor survival

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29179

Abstract: Gastric cancer has become the third most common cancer around the world. In patients with gastric cancer, the 5‐year survival rate is still low. However, the mechanism underlying gastric cancer remains largely unknown. As a… read more here.

Keywords: gastric cancer; poor survival; growth gastric; cancer cells ... See more keywords

Overexpression of signal sequence receptor γ predicts poor survival in patients with hepatocellular carcinoma.

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Published in 2018 at "Human pathology"

DOI: 10.1016/j.humpath.2018.06.014

Abstract: SSR subunit γ (SSR3), an SSR family member, is heavily involved in cell growth and differentiation and closely associated with many tumor types. However, the role of this protein in HCC remains unknown. In this… read more here.

Keywords: poor survival; hcc; ssr3 expression; hcc patients ... See more keywords

DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients

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Published in 2018 at "Oncogene"

DOI: 10.1038/s41388-018-0196-1

Abstract: Copy number alterations (CNAs) are crucial for colorectal cancer (CRC) development. In this study, DEAD box polypeptide 27 (DDX27) was identified to be highly amplified in both TCGA CRC (474/615) and primary CRC (47/103), which… read more here.

Keywords: ddx27; survival crc; colorectal cancer; dead box ... See more keywords

Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients

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Published in 2024 at "Oncogene"

DOI: 10.1038/s41388-024-02981-x

Abstract: The non-canonical translation initiation factor EIF4G2 plays essential roles in cellular stress responses via translation of selective mRNA cohorts. Currently there is limited and conflicting information regarding its involvement in cancer development and progression. Here… read more here.

Keywords: cancer; eif4g2; eif4g2 mediates; loss eif4g2 ... See more keywords

Poor Survival After Retransplantation in NASH Cirrhosis

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Published in 2019 at "Transplantation"

DOI: 10.1097/tp.0000000000002135

Abstract: Background Nonalcoholic steatohepatitis (NASH) cirrhosis is a common indication for liver transplantation (LT) in the United States. There is a paucity of data on retransplantation (re-LT) in those who were initially transplanted for NASH. Methods… read more here.

Keywords: poor survival; nash cirrhosis; survival retransplantation; nash group ... See more keywords

Lower Expression of TWEAK is Associated with Poor Survival and Dysregulate TIICs in Lung Adenocarcinoma

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Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/8661423

Abstract: Background Lung cancer remains the leading cause of cancer death worldwide, and the most subtype is lung adenocarcinoma (LUAD). Tumor-infiltrating immune cells (TIICs) greatly impact the prognosis of LUAD. Tumor necrosis factor–like weak inducer of… read more here.

Keywords: tweak; lung adenocarcinoma; expression; poor survival ... See more keywords

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia.

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Published in 2020 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-20-1579

Abstract: Clinical outcome of patients with acute myeloid leukemia (AML) is associated with cytogenetic and molecular factors and patient demographics (e.g., age and race). We compared survival of 25,523 Non-Hispanic Black and White adults with AML… read more here.

Keywords: myeloid leukemia; acute myeloid; poor survival; black patients ... See more keywords

LncRNA SNHG3 promotes cell growth by sponging miR-196a-5p and indicates the poor survival in osteosarcoma

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Published in 2019 at "International Journal of Immunopathology and Pharmacology"

DOI: 10.1177/2058738418820743

Abstract: Abnormal expression of long noncoding RNAs (lncRNAs) is closely associated with the pathogenesis of multiple malignancies, and lncRNA small nucleolar RNA host genes (SNHGs) play critical roles in tumor progression. However, the mechanism by which… read more here.

Keywords: mir 196a; snhg3; cell growth; expression ... See more keywords
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Validation of POD24 As a Robust Early Clinical Endpoint of Poor Survival in FL from 5,225 Patients on 13 Clinical Trials.

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Published in 2021 at "Blood"

DOI: 10.1182/blood.2020010263

Abstract: Observational studies and standalone trials indicate that patients with follicular lymphoma (FL) who experience disease progression within 24 months of front-line chemoimmunotherapy (POD24), have poor outcomes. We performed a pooled analysis of 13 randomized clinical… read more here.

Keywords: analysis; evaluated association; pod24; poor survival ... See more keywords

Low frequency of Vγ9Vδ2 T cells predicts poor survival in newly diagnosed acute myeloid leukemia

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Published in 2024 at "Blood Advances"

DOI: 10.1182/bloodadvances.2023011594

Abstract: Key Points • A low frequency of Vγ9Vδ2 T cells in AML is an independent predictor of poor clinical outcome.• These data provide a strong rationale for the development of consolidation protocols aimed at enhancing… read more here.

Keywords: frequency cells; cells predicts; predicts poor; poor survival ... See more keywords