Use of normalized prediction distribution errors for assessing population physiologically-based pharmacokinetic model adequacy
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DOI: 10.1007/s10928-020-09684-2
Abstract: Currently employed methods for qualifying population physiologically-based pharmacokinetic (Pop-PBPK) model predictions of continuous outcomes (e.g., concentration–time data) fail to account for within-subject correlations and the presence of residual error. In this study, we propose a… read more here.
Keywords: population physiologically; model; pop pbpk; pbpk ... See more keywords