POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912069
Abstract: Canonical inflammasomes are innate immune protein scaffolds that enable the activation of inflammatory caspase-1, and subsequently the processing and release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction of pyroptotic cell… read more here.
Keywords: msu crystal; inflammasome assembly; inflammasome activation; pop1 ... See more keywords
POP1 Facilitates Proliferation in Triple-Negative Breast Cancer via m6A-Dependent Degradation of CDKN1A mRNA
Sign Up to like & getrecommendations! Published in 2024 at "Research"
DOI: 10.34133/research.0472
Abstract: Triple-negative breast cancer (TNBC) is currently the worst prognostic subtype of breast cancer, and there is no effective treatment other than chemotherapy. Processing of precursors 1 (POP1) is the most substantially up-regulated RNA-binding protein (RBP)… read more here.
Keywords: pop1; breast cancer; cdkn1a; triple negative ... See more keywords