POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
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DOI: 10.3389/fimmu.2022.912069
Abstract: Canonical inflammasomes are innate immune protein scaffolds that enable the activation of inflammatory caspase-1, and subsequently the processing and release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction of pyroptotic cell… read more here.
Keywords: msu crystal; inflammasome assembly; inflammasome activation; pop1 ... See more keywords