Inhibition of Aβ16-22 Peptide Aggregation by Small Molecules and Their Permeation through POPC Lipid Bilayer: Insight from Molecular Dynamics Simulation Study
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DOI: 10.1021/acs.jcim.1c01366
Abstract: Alzheimer's Disease is a rapidly progressing irreversible neurodegenerative disorder characterized by neuronal cell deterioration that endangers human health. With its proper therapeutic treatment being unavailable, several research groups throughout the world are involved in designing… read more here.
Keywords: aggregation; molecular dynamics; peptide aggregation; popc lipid ... See more keywords
Cations Do Not Alter the Membrane Structure of POPC—A Lipid With an Intermediate Area
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.926591
Abstract: Combining small-angle neutron scattering (SANS), small-angle X-ray scattering (SAXS), and densitometric measurements, we have studied the interactions of the divalent cations Ca2+ and Mg2+ with the lipid vesicles prepared of a mixed-chain palmitoyl-oleoyl-phosphatidylcholine (POPC) at… read more here.
Keywords: area; membrane; popc lipid; lipid ion ... See more keywords