Population heterogeneity in microbial bioprocesses: origin, analysis, mechanisms, and future perspectives
Sign Up to like & getrecommendations! Published in 2018 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-018-1922-3
Abstract: Population heterogeneity is omnipresent in all bioprocesses even in homogenous environments. Its origin, however, is only so well understood that potential strategies like bet-hedging, noise in gene expression and division of labour that lead to… read more here.
Keywords: population heterogeneity; heterogeneity microbial; population; bioprocesses origin ... See more keywords
Effect of population heterogeneity on herd immunity and on vaccination decision making process.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2021.110795
Abstract: We study the influence of population heterogeneity on herd immunity level and on individual's vaccination decision making process. We first formulate the mathematical model in a population with two subgroups, based on different activity levels… read more here.
Keywords: herd immunity; immunity; vaccination decision; population heterogeneity ... See more keywords
Semiparametric estimation of the transformation model by leveraging external aggregate data in the presence of population heterogeneity.
Sign Up to like & getrecommendations! Published in 2022 at "Biometrics"
DOI: 10.1111/biom.13778
Abstract: Leveraging information in aggregate data from external sources to improve estimation efficiency and prediction accuracy with smaller-scale studies has drawn a great deal of attention in recent years. Yet, conventional methods often either ignore uncertainty… read more here.
Keywords: information; population heterogeneity; aggregate data; estimation ... See more keywords
Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001627
Abstract: Brain imaging research enjoys increasing adoption of supervised machine learning for single-participant disease classification. Yet, the success of these algorithms likely depends on population diversity, including demographic differences and other factors that may be outside… read more here.
Keywords: brain; brain imaging; diversity; population heterogeneity ... See more keywords
At-home dried blood spot (DBS) collection to increase population heterogeneity representation in pediatric research: An ECHO study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2023.1059107
Abstract: Self-collection of dried blood samples (DBS) in the participant's home provides an alternative to university/hospital visits for research and has the potential to improve the representation of population heterogeneity in research. This study aimed to… read more here.
Keywords: dbs; dbs collection; population heterogeneity; home ... See more keywords
Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in Large-Scale Bioreactors
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DOI: 10.3390/bioengineering4020027
Abstract: Successful scale-up of bioprocesses requires that laboratory-scale performance is equally achieved during large-scale production to meet economic constraints. In industry, heuristic approaches are often applied, making use of physical scale-up criteria that do not consider… read more here.
Keywords: large scale; population heterogeneity; scale; heterogeneity large ... See more keywords