Prioritizing Pediatric Drug Research Using Population-Level Health Data.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2016.3462
Abstract: Under the Best Pharmaceuticals for Children Act, the National Institute of Child Health and Human Development (NICHD) is tasked with updating annually a priority list of drugs requiring further study in children.1 The 2015 Priority… read more here.
Keywords: population level; use; drug; health ... See more keywords
Population-level variation in host plant response to multiple microbial mutualists.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of botany"
DOI: 10.1002/ajb2.1543
Abstract: PREMISE Multipartite mutualisms are widespread in nature, but population-level variation in these interactions is rarely quantified. In the model multipartite mutualism between legumes, arbuscular mycorrhizal (AM) fungi and rhizobia bacteria, host responses to microbial partners… read more here.
Keywords: population level; response; plant; plant response ... See more keywords
The Impact of Comprehensive Community Initiatives on Population-Level Child, Youth, and Family Outcomes: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of community psychology"
DOI: 10.1002/ajcp.12398
Abstract: Comprehensive community initiatives (CCIs) represent a popular method for creating systemic change, yet there is a dearth of evidence on their effectiveness (Zaff, Pufall Jones, Donlan, Lin, & Anderson, 2016). This article presents a systematic… read more here.
Keywords: population level; community; systematic review; community initiatives ... See more keywords
Species specificity and intraspecific variation in the chemical profiles of Heliconius butterflies across a large geographic range
Sign Up to like & getrecommendations! Published in 2020 at "Ecology and Evolution"
DOI: 10.1002/ece3.6079
Abstract: Abstract In many animals, mate choice is important for the maintenance of reproductive isolation between species. Traits important for mate choice and behavioral isolation are predicted to be under strong stabilizing selection within species; however,… read more here.
Keywords: heliconius butterflies; variation chemical; chemical profiles; population level ... See more keywords
Linking population‐level and microevolutionary processes to understand speciation dynamics at the macroevolutionary scale
Sign Up to like & getrecommendations! Published in 2021 at "Ecology and Evolution"
DOI: 10.1002/ece3.7511
Abstract: Abstract Although speciation dynamics have been described for several taxonomic groups in distinct geographic regions, most macroevolutionary studies still lack a detailed mechanistic view on how or why speciation rates change. To help partially fill… read more here.
Keywords: microevolutionary processes; population level; dynamics macroevolutionary; linking population ... See more keywords
The Use of Mechanistic Population Models in Metal Risk Assessment: Combined Effects of Copper and Food Source on Lymnaea stagnalis Populations.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4391
Abstract: Environmental risk assessment (ERA) of chemicals aims to protect populations, communities, and ecosystems. Population models are considered more frequent in ERA because they can bridge the gap between the individual and the population level. Lymnaea… read more here.
Keywords: population level; risk assessment; chemistry; level ... See more keywords
Investigating Population‐Level Toxicity of the Antidepressant Citalopram in Harpacticoid Copepods Using In Vivo Methods and Bioenergetics‐Based Population Modeling
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5599
Abstract: Recent research has revealed various lethal and sublethal effects of the selective serotonin reuptake inhibitor citalopram hydrobromide on the harpacticoid copepod Nitocra spinipes. In the present study, an individual‐based model (IBM) grounded in the dynamic… read more here.
Keywords: citalopram; population level; bioenergetics based; model ... See more keywords
Population‐level utilisation of neoadjuvant radiotherapy for the treatment of rectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26872
Abstract: International clinical guidelines recommend long‐ or short‐course neoadjuvant radiotherapy for locally advanced rectal cancer. This study aims to examine variation in the use of neoadjuvant radiotherapy for rectal cancer and identify patient and hospital factors… read more here.
Keywords: rectal cancer; neoadjuvant radiotherapy; level utilisation; population level ... See more keywords
How does within‐host dynamics affect population‐level dynamics? Insights from an immuno‐epidemiological model of malaria
Sign Up to like & getrecommendations! Published in 2017 at "Mathematical Methods in The Applied Sciences"
DOI: 10.1002/mma.4466
Abstract: Malaria is one of the most common mosquito-borne diseases widespread in the tropical and subtropical regions. Few models coupling the within-host malaria dynamics with the between-host mosquito-human dynamics have been developed. In this paper, by… read more here.
Keywords: population level; reproduction; within host; model ... See more keywords
Evaluating the population‐level effects of oxycodone restrictions on prescription opioid utilization in Ontario
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5442
Abstract: To investigate the impact of restrictions on access to long acting oxycodone on prescription opioid use and opioid‐related harms. read more here.
Keywords: prescription opioid; prescription; population level; level effects ... See more keywords
Single Cell and Population Level Analysis of HCA Data.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7357-6_15
Abstract: High Content Analysis instrumentation has undergone tremendous hardware advances in recent years. It is now possible to obtain images of hundreds of thousands to millions of individual objects, across multiple wells, channels, and plates, in… read more here.
Keywords: single cell; analysis hca; population level; level analysis ... See more keywords