Non-HDL-C levels and residual cardiovascular risk: Do population-specific precision approaches offer advantages?
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.05.010
Abstract: Since the initial discovery of the links between dietary fats, blood lipids and coronary heart disease (CHD) risks nearly eight decades ago [1, 2], extensive research has been conducted in this area and the risk… read more here.
Keywords: hdl levels; risk; non hdl; population specific ... See more keywords
Evaluation of Lou et al.: Proposed benefits of a population-specific genome reference.
Sign Up to like & getrecommendations! Published in 2022 at "Cell systems"
DOI: 10.1016/j.cels.2022.03.005
Abstract: One snapshot of the peer review process for "Haplo-type-resolved de novo assembly of a Tujia genome suggests the necessity for high-quality population-specific genome references" (Lou et al., 2022). read more here.
Keywords: population specific; evaluation lou; proposed benefits; lou proposed ... See more keywords
Sex estimation from measurements of the calcaneus: Applications for personal identification in Thailand.
Sign Up to like & getrecommendations! Published in 2017 at "Forensic science international"
DOI: 10.1016/j.forsciint.2017.06.035
Abstract: As a coastal region, Thailand has been significantly affected by climate change. The impacts of climate change in Thailand - temperature increase, rising sea levels, and violent flooding - are predicted to multiply in both… read more here.
Keywords: thailand; population; sex estimation; population specific ... See more keywords
BRAHMA: Population specific T1, T2, and FLAIR weighted brain templates and their impact in structural and functional imaging studies.
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2019.12.009
Abstract: Differences in brain morphology across population groups necessitate creation of population-specific Magnetic Resonance Imaging (MRI) brain templates for interpretation of neuroimaging data. Variations in the neuroanatomy in a genetically heterogeneous population make the development of… read more here.
Keywords: template; brain templates; flair; population specific ... See more keywords
Alterations of Brain Networks in Alzheimer’s Disease and Mild Cognitive Impairment: A Resting State fMRI Study Based on a Population-specific Brain Template
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.10.023
Abstract: This study aimed to investigate the alterations in brain networks in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) based on a population-specific brain template. Previous studies on AD brain networks using graph… read more here.
Keywords: based population; specific brain; graph; brain networks ... See more keywords
Systematic review of the evidence on the epidemiology of herpes zoster: incidence in the general population and specific subpopulations in Spain.
Sign Up to like & getrecommendations! Published in 2019 at "Public health"
DOI: 10.1016/j.puhe.2018.10.015
Abstract: OBJECTIVES Herpes zoster (HZ) is an important cause of morbidity around the world, especially among the adult population aged >50 years. STUDY DESIGN A systematic review of the literature (up to October 31, 2016) was… read more here.
Keywords: general population; herpes zoster; incidence general; epidemiology ... See more keywords
A method to customize population-specific arrays for genome-wide association testing
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Human Genetics"
DOI: 10.1038/ejhg.2016.152
Abstract: As an example of optimizing population-specific genotyping assays using a whole-genome sequence reference set, we detail the approach that followed to design the Axiom-NL array which is characterized by an improved imputation backbone based on… read more here.
Keywords: genome wide; array; snps; association ... See more keywords
Population-specific signatures of intra-individual mitochondrial DNA heteroplasmy and their potential evolutionary advantages
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-019-56918-6
Abstract: Heteroplasmy is the existence of more than one mitochondrial DNA (mtDNA) variant within a cell. The evolutionary mechanisms of heteroplasmy are not fully understood, despite being a very common phenomenon. Here we combined heteroplasmy measurements… read more here.
Keywords: mitochondrial dna; heteroplasmy; population; population specific ... See more keywords
Population-Specific Genetic and Expression Differentiation in Europeans
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa021
Abstract: Abstract Much of the enormous phenotypic variation observed across human populations is thought to have arisen from events experienced as our ancestors peopled different regions of the world. However, little is known about the genes… read more here.
Keywords: expression differentiation; population; genetic expression; population specific ... See more keywords
The Population-Specific Impact of Neandertal Introgression on Human Disease
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa250
Abstract: Abstract Since the discovery of admixture between modern humans and Neandertals, multiple studies investigated the effect of Neandertal-derived DNA on human disease and nondisease phenotypes. These studies have linked Neandertal ancestry to skin- and hair-related… read more here.
Keywords: neandertal dna; specific impact; disease; population specific ... See more keywords
GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddx071
Abstract: Abstract Vitamin B12 is an important cofactor in one‐carbon metabolism whose dysregulation is associated with various clinical conditions. Indians have a high prevalence of B12 deficiency but little is known about the genetic determinants of… read more here.
Keywords: fut6 associated; plasma b12; concentrations indians; population specific ... See more keywords