Cost-effectiveness of Population-Wide Genomic Screening for Hereditary Breast and Ovarian Cancer in the United States
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.22874
Abstract: Key Points Question Is it cost-effective to implement population-wide genomic screening for hereditary breast and ovarian cancer (HBOC)? Findings This decision analytical model study found that genomic screening for HBOC among unselected women may be… read more here.
Keywords: genomic screening; screening; screening hereditary; population wide ... See more keywords
Population‐wide differentials in HIV service access and outcomes in the Western Cape for men as compared to women, South Africa: 2008 to 2018: a cohort analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25530
Abstract: Few studies have systematically described population‐level differences comparing men and women across the continuum of routine HIV care. This study quantifies differentials in HIV care, treatment and mortality outcomes for men and women over time… read more here.
Keywords: south africa; differentials hiv; hiv service; population wide ... See more keywords
A Population‐Wide Exploration of the THAP11 CAG Repeat Size and Structure in the 100,000 Genomes Project and UK Biobank
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders"
DOI: 10.1002/mds.30073
Abstract: A CAG repeat expansion in THAP11 was recently found to be associated with spinocerebellar ataxia in two Chinese families. Expanded repeats ranged from 45 to 100 units, with CAA sequence interruptions in the 5′ region and… read more here.
Keywords: cag repeat; thap11; population wide; cag ... See more keywords
Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy
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DOI: 10.1038/s41591-020-0883-7
Abstract: In Italy, 128,948 confirmed cases and 15,887 deaths of people who tested positive for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 pandemic requires implementation of multiple population-wide strategies, including social… read more here.
Keywords: implementation; population wide; model; sars cov ... See more keywords
Linking progression patterns in ischaemic heart disease to comorbidities and genetics by integrated analysis of electronic health records and population-wide registries
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.3496
Abstract: Ischaemic heart disease (IHD) is a diverse phenotype conventionally characterized by presence of the cardinal symptom, angina pectoris (fig. 1). Evidence of scientific value in electronic health records (EHRs) is accumulating although point of care… read more here.
Keywords: progression patterns; genetics; population wide; disease ... See more keywords
Salt and hypertension: what do we know?
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Cardiology"
DOI: 10.1097/hco.0000000000000525
Abstract: Purpose of review To evaluate the evidence for population-wide sodium restriction. Recent findings The recommendations for population-wide sodium restriction largely rely on one surrogate marker (blood pressure). However, recent evidence suggests that when looking beyond… read more here.
Keywords: salt hypertension; sodium restriction; population wide; sodium ... See more keywords
Prevalence and Mortality Associated with Bloodstream Organisms: a Population-Wide Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02429-21
Abstract: Bloodstream infections (BSIs) represent a substantial mortality risk, yet most studies are limited to select pathogens or populations. The aim of this study was to describe the population-wide prevalence of BSIs and examine the associated… read more here.
Keywords: population wide; mortality; population; study ... See more keywords
SAFety, Effectiveness of care and Resource use among Australian Hospitals (SAFER Hospitals): a protocol for a population-wide cohort study of outcomes of hospital care
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DOI: 10.1136/bmjopen-2019-035446
Abstract: Introduction Despite global concerns about the safety and quality of health care, population-wide studies of hospital outcomes are uncommon. The SAFety, Effectiveness of care and Resource use among Australian Hospitals (SAFER Hospitals) study seeks to… read more here.
Keywords: safer hospitals; use; safety; study ... See more keywords
Abstract FR521: Population-wide blood pressure reduction and estimated hypertension incidence, cardiovascular disease events, and healthcare costs in Black adults: A simulation using Jackson Heart Study data
Sign Up to like & getrecommendations! Published in 2025 at "Hypertension"
DOI: 10.1161/hyp.82.suppl_1.fr521
Abstract: Background: Black adults in the U.S. have higher rates of hypertension compared to White adults, contributing to disparities in cardiovascular disease (CVD). Quantifying the health and economic impact of population-wide systolic blood pressure (SBP) reductions… read more here.
Keywords: healthcare costs; cvd events; hypertension; black adults ... See more keywords
Abstract 67: Risk and Time-Course of Post-Stroke Dementia: A Population-Wide Cohort Study, 2002-2022
Sign Up to like & getrecommendations! Published in 2024 at "Stroke"
DOI: 10.1161/str.55.suppl_1.67
Abstract: Background: People with acute stroke are at high risk of dementia. Population-wide data on the risk and time-course of dementia after stroke are lacking. Methods: We conducted a population-wide analysis of over 15 million people… read more here.
Keywords: dementia; stroke; time; risk ... See more keywords
Population-wide administration of single dose rifampicin for leprosy prevention in isolated communities: a three year follow-up feasibility study in Indonesia
Sign Up to like & getrecommendations! Published in 2018 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-018-3233-3
Abstract: BackgroundIndonesia ranking third in the world, regarding leprosy burden. Chemoprophylaxis is effective in reducing risk of developing leprosy among contacts. ‘Blanket approach’ is an operational strategy for leprosy post-exposure prophylaxis in which all members of… read more here.
Keywords: dose rifampicin; prevention isolated; population wide; leprosy prevention ... See more keywords