Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00024
Abstract: Comprehensive phosphoproteomic analysis of small populations of cells remains a daunting task due primarily to the insufficient MS signal intensity from low concentrations of enriched phosphopeptides. Isobaric labeling has a unique multiplexing feature where the… read more here.
Keywords: comprehensive quantitative; populations cells; small populations; quantitative phosphoproteomic ... See more keywords
Simultaneous Multiparameter Cellular Energy Metabolism Profiling of Small Populations of Cells
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DOI: 10.1038/s41598-018-22599-w
Abstract: Functional and genomic heterogeneity of individual cells are central players in a broad spectrum of normal and disease states. Our knowledge about the role of cellular heterogeneity in tissue and organism function remains limited due… read more here.
Keywords: populations cells; energy metabolism; metabolism profiling; profiling small ... See more keywords
Kinetics of biochemical sensing by single cells and populations of cells.
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DOI: 10.1103/physreve.96.042413
Abstract: We investigate the collective stationary sensing using N communicative cells, which involves surface receptors, diffusive signaling molecules, and cell-cell communication messengers. We restrict the scenarios to the signal-to-noise ratios (SNRs) for both strong communication and… read more here.
Keywords: sensing single; populations cells; biochemical sensing; single cells ... See more keywords