Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival
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DOI: 10.1038/s41598-020-73150-9
Abstract: Xenotransplantation using pig organs has achieved survival times up to 195 days in pig orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an improved immunosuppressive regimen, non-ischaemic preservation with continuous perfusion… read more here.
Keywords: impact porcine; orthotopic; cytomegalovirus; cytomegalovirus long ... See more keywords
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?
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DOI: 10.1111/xen.12775
Abstract: The potential for a donor‐derived transmission of porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV) to the recipient has been recognized since pigs were considered candidate donors for xenotransplantation. This review gives a short description of the viral properties… read more here.
Keywords: xenotransplantation; porcine; porcine cytomegalovirus; pcmv prv ... See more keywords
First transplantation of a pig heart from a multiple gene-modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs.
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DOI: 10.1111/xen.12800
Abstract: The porcine cytomegalovirus (PCMV) is actually a porcine roseolovirus (PRV).1 As the official International Committee on Taxonomy of Viruses (ITCV) name, suid betaherpesvirus 2 (SuBHV2),2 is not widely used, the abbreviation (PCMV/PRV) will be used… read more here.
Keywords: pig; pig heart; pcmv prv; heart ... See more keywords
Effective Detection of Porcine Cytomegalovirus Using Non-Invasively Taken Samples from Piglets
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DOI: 10.3390/v9010009
Abstract: Shortage of human organs forced the development of xenotransplantation using cells, tissues, and organs from pigs. Xenotransplantation may be associated with the transmission of porcine zoonotic microorganisms, among them the porcine cytomegalovirus (PCMV). To prevent… read more here.
Keywords: detection; real time; time pcr; porcine ... See more keywords