The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil.
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DOI: 10.1021/acs.biochem.1c00096
Abstract: Dihydropyrimidine dehydrogenase (DPD) is a complex enzyme that reduces the 5,6-vinylic bond of pyrimidines, uracil, and thymine. 5-Fluorouracil (5FU) is also a substrate for DPD and a common chemotherapeutic agent used to treat numerous cancers.… read more here.
Keywords: interaction porcine; dihydropyrimidine dehydrogenase; dehydrogenase; cross linking ... See more keywords