Porcine endogenous retrovirus envelope coated baculoviral DNA vaccine against porcine reproductive and respiratory syndrome virus
Sign Up to like & getrecommendations! Published in 2018 at "Animal Biotechnology"
DOI: 10.1080/10495398.2018.1531014
Abstract: Abstract PERV is a major virus concerning xenotransplantation study. However, the interesting part is that PERV is present in all kinds of pigs without pathogenicity and immune response. Furthermore, since pig cells have receptors for… read more here.
Keywords: dna; porcine endogenous; respiratory; vaccine ... See more keywords
Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets
Sign Up to like & getrecommendations! Published in 2017 at "Xenotransplantation"
DOI: 10.1111/xen.12311
Abstract: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans. It has been… read more here.
Keywords: pig; retrovirus expression; characterization porcine; porcine endogenous ... See more keywords
Limited environmental stability of infectious porcine endogenous retrovirus type C; Usage of reverse transcriptase in combination with viral RNA as markers for infectious virus
Sign Up to like & getrecommendations! Published in 2022 at "Xenotransplantation"
DOI: 10.1111/xen.12738
Abstract: Porcine endogenous retroviruses (PERVs) are an integral part of the pig genome with infectious potential, as shown in vitro. read more here.
Keywords: infectious porcine; limited environmental; environmental stability; stability infectious ... See more keywords
Screening and Identification of the First Non-CRISPR/Cas9-Treated Chinese Miniature Pig With Defective Porcine Endogenous Retrovirus pol Genes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.797608
Abstract: Pig to human xenotransplantation is considered to be a possible approach to alleviate the shortage of human allografts. Porcine endogenous retrovirus (PERV) is the most significant pathogen in xenotransplantation. We screened for pigs that consistently… read more here.
Keywords: pol genes; porcine endogenous; non transmitting; endogenous retrovirus ... See more keywords
High Prevalence of Recombinant Porcine Endogenous Retroviruses (PERV-A/Cs) in Minipigs: A Review on Origin and Presence
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DOI: 10.3390/v13091869
Abstract: Minipigs play an important role in biomedical research and they have also been used as donor animals for preclinical xenotransplantations. Since zoonotic microorganisms including viruses can be transmitted when pig cells, tissues or organs are… read more here.
Keywords: high prevalence; perv; porcine endogenous; endogenous retroviruses ... See more keywords
Regulation of porcine endogenous retrovirus by dual LTR1+2 (Long Terminal Region) miRNA in primary porcine kidney cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.2019.20.e50
Abstract: Porcine endogenous retroviruses (PERVs) integrate into germline DNA as proviral genome that enables vertical transmission from parents to their offspring. The provirus usually survives as part of the host genome rather than as an infectious… read more here.
Keywords: kidney cells; porcine; porcine endogenous; primary porcine ... See more keywords
Selective human cells in vitro transduction with porcine endogenous retrovirus (PERV).
Sign Up to like & getrecommendations! Published in 2022 at "Acta virologica"
DOI: 10.4149/av_2022_201
Abstract: Porcine xenograft transplantation raises concerns in humans about the risk of infection with porcine endogenous retroviruses (PERV) as they are an integral part of the pig genome and are therefore very difficult to exclude. In… read more here.
Keywords: human cells; sequence; perv; porcine endogenous ... See more keywords