Anti-inflammatory and anti-osteoarthritis effects of Cm-02 and Ck-02.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.07.036
Abstract: Osteoarthritis (OA) is a common degenerative joint disease characterized by progressive deterioration of articular cartilage. There have been reports that small molecule inhibitors have anti-osteoarthritis effects; however, the effects of 3-(4-chloro-2-fluorophenyl)-6-(2,4-difluorophenyl)-2H-benzo[e] [1,3]oxazine-2,4(3H)-dione (Cm-02) and 6-(2,4-difluorophenyl)-3-(3,4-difluorophenyl)-2H-benzo[e]… read more here.
Keywords: anti inflammatory; anti osteoarthritis; osteoarthritis; inflammatory anti ... See more keywords
Anticonvulsant effects after grafting of rat, porcine, and human mesencephalic neural progenitor cells into the rat subthalamic nucleus
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2018.09.004
Abstract: ABSTRACT Cell transplantation based therapy is a promising strategy for treating intractable epilepsies. Inhibition of the subthalamic nucleus (STN) or substantia nigra pars reticulata (SNr) is a powerful experimental approach for remote control of different… read more here.
Keywords: subthalamic nucleus; cell; anticonvulsant effects; effects grafting ... See more keywords
Transfer Function for Relative Blast Overpressure Through Porcine and Human Skulls In Situ.
Sign Up to like & getrecommendations! Published in 2021 at "Military medicine"
DOI: 10.1093/milmed/usab412
Abstract: INTRODUCTION The overarching objective of the Office of Naval Research sponsored Blast Load Assessment Sense and Test (BLAST) program was to quantify neurofunctional risk from repeated blast exposure. However, human studies have limitations in data… read more here.
Keywords: blast; methodology; brain; transfer ... See more keywords
Comparison of Neonatal and Adult Fibrin Clot Properties between Porcine and Human Plasma
Sign Up to like & getrecommendations! Published in 2020 at "Anesthesiology"
DOI: 10.1097/aln.0000000000003165
Abstract: Background: Recent studies suggest that adult-specific treatment options for fibrinogen replacement during bleeding may be less effective in neonates. This is likely due to structural and functional differences found in the fibrin network between adults… read more here.
Keywords: microscopy; adult; porcine human; neonatal porcine ... See more keywords
First porcine to human kidney transplantation performed in the United States.
Sign Up to like & getrecommendations! Published in 2021 at "Artificial organs"
DOI: 10.1111/aor.14139
Abstract: In an operation that lasted a little over 2 h, surgeons at New York University Langone Health transplanted a porcine kidney into a human patient without signs of early rejection. This is a landmark achievement… read more here.
Keywords: transplantation performed; porcine human; human kidney; kidney transplantation ... See more keywords
Porcine to Human Heart Transplantation: Is Clinical Application Now Appropriate?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/2534653
Abstract: Cardiac xenotransplantation (CXTx) is a promising solution to the chronic shortage of donor hearts. Recent advancements in immune suppression have greatly improved the survival of heterotopic CXTx, now extended beyond 2 years, and life-supporting kidney… read more here.
Keywords: preclinical studies; life supporting; human heart; clinical cxtx ... See more keywords
Aquaporin 4 is not present in normal porcine and human lamina cribrosa
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268541
Abstract: Aquaporin 4 is absent from astrocytes in the rodent optic nerve head, despite high expression in the retina and myelinated optic nerve. The purpose of this study was to quantify regional aquaporin channel expression in… read more here.
Keywords: lamina; optic nerve; expression; mon ... See more keywords