Articles with "porcine model" as a keyword



The percutaneous toxicokinetics of VX in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant

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Published in 2018 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.3542

Abstract: This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for the decontamination of superficial, nerve agent‐contaminated wounds. Anaesthetized animals were randomly assigned to either control (n = 7),… read more here.

Keywords: damaged skin; porcine model; decontamination; skin porcine ... See more keywords

A bio‐artificial renal epithelial cell system conveys survival advantage in a porcine model of septic shock

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Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.1961

Abstract: Renal cell therapy using the hollow fiber based renal assist device (RAD) improved survival time in an animal model of septic shock (SS) through the amelioration of cardiac and vascular dysfunction. Safety and ability of… read more here.

Keywords: porcine model; model; brecs; therapy ... See more keywords

Large Porcine Model of Profound Acute Ischemic Cardiogenic Shock.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8597-5_27

Abstract: Cardiogenic shock is one of the leading causes of death following acute myocardial infarction affecting 10% of patients with large myocardial infarcts with a subsequent mortality rate of 50%. Here we describe a large porcine… read more here.

Keywords: porcine model; large porcine; acute ischemic; cardiogenic shock ... See more keywords

A novel porcine model of thrombotic myocardial infarction with cardiac dysfunction sensitive to dual antiplatelet therapy

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.07.020

Abstract: ABSTRACT Few effective porcine models of myocardial infarction (MI) related to platelet thrombus formation are available. In this study, we established a novel porcine MI model and examined the effect of dual antiplatelet therapy (DAPT)… read more here.

Keywords: volume; porcine model; group; model ... See more keywords

Atrial myofibroblast activation and connective tissue formation in a porcine model of atrial fibrillation and reduced left ventricular function

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Published in 2017 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.05.025

Abstract: Aims: Atrial fibrillation (AF) is associated with fibrosis that slows electrical conduction and causes perpetuation of the arrhythmia. The molecular characterization of AF pathophysiology may provide novel therapeutic options. This study was designed to elucidate… read more here.

Keywords: atrial fibrillation; model atrial; myofibroblast activation; porcine model ... See more keywords

Use of a novel docosahexaenoic acid formulation vs control in a neonatal porcine model of short bowel syndrome leads to greater intestinal absorption and higher systemic levels of DHA.

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Published in 2017 at "Nutrition research"

DOI: 10.1016/j.nutres.2017.02.004

Abstract: Infants with short bowel syndrome (SBS) are at high risk for malabsorption, malnutrition, and failure to thrive. The objective of this study was to evaluate in a porcine model of SBS, the systemic absorption of… read more here.

Keywords: absorption; levels dha; porcine model; control ... See more keywords

Dynamic Quantitative Iodine Myocardial Perfusion Imaging with Dual-Layer CT using a Porcine Model

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-52458-1

Abstract: Ischemic heart disease is the globally leading cause of death. When using coronary CT angiography, the functional hemodynamics within the myocardium remain uncertain. In this study myocardial CT perfusion imaging using iodine contrast agent demonstrated… read more here.

Keywords: perfusion; myocardial perfusion; perfusion imaging; porcine model ... See more keywords

Radionecrosis and cellular changes in small volume stereotactic brain radiosurgery in a porcine model

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-72876-w

Abstract: Stereotactic radiosurgery (SRS) has proven an effective tool for the treatment of brain tumors, arteriovenous malformation, and functional conditions. However, radiation-induced therapeutic effect in viable cells in functional SRS is also suggested. Evaluation of the… read more here.

Keywords: porcine model; small volume; radiosurgery; brain ... See more keywords

Gasless transvaginal natural orifice transluminal endoscopic surgery for hysterectomy and salpingectomy on a robot platform with flexible devices in a porcine model

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-55576-7

Abstract: In this report, we described a new technique of gasless V-NOTES for hysterectomy and salpingectomy on a robotic platform with flexible devices in a porcine model. As a result, the gynecological procedures were successfully completed.… read more here.

Keywords: platform flexible; flexible devices; porcine model; hysterectomy salpingectomy ... See more keywords
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Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning

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Published in 2021 at "Clinical Toxicology"

DOI: 10.1080/15563650.2020.1870691

Abstract: Abstract Objectives The purpose of this study is the development of a porcine model of carbon monoxide (CO) poisoning to investigate alterations in brain and heart mitochondrial function. Design Two group large animal model of… read more here.

Keywords: porcine model; mitochondrial function; group; tissue ... See more keywords

Percutaneous Externally Assembled Laparoscopic vs Laparoendoscopic Single-Site Nephrectomy in a Porcine Model: A Prospective, Randomized, Blinded, Study.

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Published in 2017 at "Journal of endourology"

DOI: 10.1089/end.2016.0615

Abstract: OBJECTIVE To compare the outcomes between laparoendoscopic single-site (LESS) and a novel percutaneous externally assembled laparoscopic (PEAL) nephrectomy in an in vivo porcine model. MATERIALS AND METHODS Ten female farm pigs were randomized to LESS… read more here.

Keywords: porcine model; single site; model; percutaneous externally ... See more keywords