Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4
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DOI: 10.1080/21505594.2022.2107646
Abstract: ABSTRACT Porcine rotavirus (PoRV) is an important pathogen, leading to the occurrence of viral diarrhoea . As the infection displays obvious enterotropism, intestinal mucosal immunity is the significant line of defence against pathogen invasion. Moreover,… read more here.
Keywords: porcine rotavirus; auxotrophic lactobacillus; crispr cas9d10a; cas9d10a system ... See more keywords
Development of a droplet digital PCR assay for detection of group A porcine rotavirus
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DOI: 10.3389/fvets.2023.1113537
Abstract: Group A porcine rotavirus (PoRVA) is an important pathogen of acute enteritis in piglets, which has caused severe economic losses in the pig industry worldwide. A convenient, sensitive and specific diagnosis method is an urgent… read more here.
Keywords: group porcine; porcine rotavirus; detection; pcr ... See more keywords
Molecular epidemiological investigation of group A porcine rotavirus in East China
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DOI: 10.3389/fvets.2023.1138419
Abstract: Group A porcine rotavirus (RVA) is a serious threat to the breeding industry worldwide, which was associated with severe diarrhea in piglets. However, the prevalence and molecular characterizations of RVA circulating in farms of East… read more here.
Keywords: east china; group porcine; porcine rotavirus;
Auxotrophic Lactobacillus Expressing Porcine Rotavirus VP4 Constructed Using CRISPR-Cas9D10A System Induces Effective Immunity in Mice
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DOI: 10.3390/vaccines10091510
Abstract: Porcine rotavirus (PoRV) mainly causes acute diarrhea in piglets under eight weeks of age and has potentially high morbidity and mortality rates. As vaccine carriers for oral immunization, lactic acid bacteria (LAB) are an ideal… read more here.
Keywords: porcine rotavirus; vp4; alr vp4; alr ... See more keywords