Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2107646
Abstract: ABSTRACT Porcine rotavirus (PoRV) is an important pathogen, leading to the occurrence of viral diarrhoea . As the infection displays obvious enterotropism, intestinal mucosal immunity is the significant line of defence against pathogen invasion. Moreover,… read more here.
Keywords: porcine rotavirus; auxotrophic lactobacillus; crispr cas9d10a; cas9d10a system ... See more keywords
Development of a droplet digital PCR assay for detection of group A porcine rotavirus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2023.1113537
Abstract: Group A porcine rotavirus (PoRVA) is an important pathogen of acute enteritis in piglets, which has caused severe economic losses in the pig industry worldwide. A convenient, sensitive and specific diagnosis method is an urgent… read more here.
Keywords: group porcine; porcine rotavirus; detection; pcr ... See more keywords
Molecular epidemiological investigation of group A porcine rotavirus in East China
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DOI: 10.3389/fvets.2023.1138419
Abstract: Group A porcine rotavirus (RVA) is a serious threat to the breeding industry worldwide, which was associated with severe diarrhea in piglets. However, the prevalence and molecular characterizations of RVA circulating in farms of East… read more here.
Keywords: east china; group porcine; porcine rotavirus;
Establishment of a reverse genetics system for an epidemic strain of porcine rotavirus JXAY01 type G5P[23]I12
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DOI: 10.3389/fvets.2024.1512327
Abstract: Porcine rotavirus is one of the most important pathogens causing diarrhea in newborn piglets, and the genome of this virus contains 11 double-stranded RNA segments, which are easy to be recombined among strains to produce… read more here.
Keywords: genetics; system; jxay01; porcine rotavirus ... See more keywords
Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter via Reverse Genetics
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DOI: 10.3390/v16030411
Abstract: Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in infants and the young of many economically important animals. Although vaccines against porcine rotavirus exist, both live oral and inactivated, their effectiveness in preventing… read more here.
Keywords: rotavirus; genetics; porcine rotavirus; reverse genetics ... See more keywords
Auxotrophic Lactobacillus Expressing Porcine Rotavirus VP4 Constructed Using CRISPR-Cas9D10A System Induces Effective Immunity in Mice
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DOI: 10.3390/vaccines10091510
Abstract: Porcine rotavirus (PoRV) mainly causes acute diarrhea in piglets under eight weeks of age and has potentially high morbidity and mortality rates. As vaccine carriers for oral immunization, lactic acid bacteria (LAB) are an ideal… read more here.
Keywords: porcine rotavirus; vp4; alr vp4; alr ... See more keywords
Isolation, Genomic Characterization and Evolution of Six Porcine Rotavirus A Strains in a Pig Farming Group
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DOI: 10.3390/vetsci11090436
Abstract: Simple Summary Porcine rotavirus re-emerged in recent years in China. In this study, we analyzed the genomic characterizations of six porcine rotavirus. A strains (PoRVA) isolated from three sow farms in a company at different… read more here.
Keywords: evolution; rotavirus; porcine rotavirus; six porcine ... See more keywords