Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs.
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DOI: 10.1016/j.ydbio.2016.11.023
Abstract: Wnt signaling has been shown to be important in orchestrating proper development of the female reproductive tract. In the uterus, six members of the Wnt family are expressed in the neonatal endometrium and deletion of… read more here.
Keywords: wnt signaling; wnt; porcupine dependent; dependent wnt ... See more keywords
Porcupine-dependent wnt activity within the uterine epithelium is essential for fertility
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DOI: 10.1093/biolre/iox119
Abstract: Abstract The secretion of mammalian Wnt ligands within the cell is dependent on the activity of Porcupine, a gene located on the X-chromosome that encodes for a membrane-bound O-acyl transferase. Here, we report that postnatal… read more here.
Keywords: porcupine; wnt; porcupine dependent; epithelium ... See more keywords