Articles with "pore activity" as a keyword



Lipid unsaturation promotes BAX and BAK pore activity during apoptosis

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-49067-6

Abstract: BAX and BAK are proapoptotic members of the BCL2 family that directly mediate mitochondrial outer membrane permeabilition (MOMP), a central step in apoptosis execution. However, the molecular architecture of the mitochondrial apoptotic pore remains a… read more here.

Keywords: bax bak; lipid unsaturation; apoptosis; pore activity ... See more keywords