Affinity Isolation of Endogenous Saccharomyces Cerevisiae Nuclear Pore Complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2337-4_1
Abstract: Studying protein complexes in vitro requires the production of a relatively pure sample that maintains the full complement, native organization, and function of that complex. This can be particularly challenging to achieve for large, multi-component,… read more here.
Keywords: pore complexes; nuclear pore; affinity; cerevisiae nuclear ... See more keywords
Nuclear pore complexes and regulation of gene expression.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2016.12.006
Abstract: Nuclear pore complexes (NPCs), are large multiprotein channels that penetrate the nuclear envelope connecting the nucleus to the cytoplasm. Accumulating evidence shows that besides their main role in regulating the exchange of molecules between these… read more here.
Keywords: pore complexes; gene expression; nuclear pore; gene ... See more keywords
Nuclear Pore Complexes Are Key Regulators of Oligodendrocyte Differentiation and Function
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DOI: 10.1016/j.neuron.2019.04.025
Abstract: Increasing evidence points to nuclear pore complexes as important regulators of cell fate and tissue homeostasis. A recent report by Liu et al. (2019) in this issue of Neuron uncovers that nucleoporin Seh1 is required for… read more here.
Keywords: complexes key; pore complexes; oligodendrocyte differentiation; nuclear pore ... See more keywords
Nuclear Pore Complexes: A Scaffold Regulating Developmental Transcription?
Sign Up to like & getrecommendations! Published in 2017 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.07.002
Abstract: Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as scaffolds that recruit the transcription… read more here.
Keywords: transcription; pore complexes; complexes scaffold; scaffold regulating ... See more keywords
Yeast and Human Nuclear Pore Complexes: Not So Similar After All.
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DOI: 10.1016/j.tcb.2018.06.004
Abstract: Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies… read more here.
Keywords: complexes similar; pore complexes; human nuclear; nuclear pore ... See more keywords
Re: Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000096
Abstract: available at http://www.ncbi.nlm.nih.gov/pubmed/30100187 Editorial Comment: The authors aimed to study if specific nucleoporins and nuclear pore complexes-nucleoporin based mechanisms contribute to prostate cancer aggressiveness. They found that the composition of nuclear pore complexes is substantially… read more here.
Keywords: pore complexes; nuclear pore; cancer; prostate cancer ... See more keywords
Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in the ciliate Tetrahymena
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Science"
DOI: 10.1242/jcs.199398
Abstract: ABSTRACT The nuclear pore complex (NPC), a gateway for nucleocytoplasmic trafficking, is composed of ∼30 different proteins called nucleoporins. It remains unknown whether the NPCs within a species are homogeneous or vary depending on the… read more here.
Keywords: pore complexes; mic npcs; compositionally distinct; ciliate tetrahymena ... See more keywords