N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake
Sign Up to like & getrecommendations! Published in 2017 at "Purinergic Signalling"
DOI: 10.1007/s11302-017-9598-8
Abstract: The P2X7 receptor is a frequently studied member of the purinergic receptor family signalling via channel opening and membrane pore formation. Fluorescent imaging is an important molecular method for studying cellular receptor expression and localization.… read more here.
Keywords: human p2x7; channel opening; receptor; p2x7 receptor ... See more keywords
Pore formation by pore forming membrane proteins towards infections.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2021.09.001
Abstract: Over the last 25 years, the biology of membrane proteins, including the PFPs-membranes interactions is seeking attention for the development of successful drug molecules against a number of infectious diseases. Pore forming toxins (PFTs), the… read more here.
Keywords: membrane proteins; pore forming; pore formation; biology ... See more keywords
Mechanisms of pore formation in hydrogel scaffolds textured by freeze-drying.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.05.070
Abstract: Whereas freeze-drying is a widely used method to produce porous hydrogel scaffolds, the mechanisms of pore formation involved in this process remained poorly characterized. To explore this, we focused on a cross-linked polysaccharide-based hydrogel developed… read more here.
Keywords: freeze drying; hydrogel; mechanisms pore; pore formation ... See more keywords
Biophysical Characterization of Membrane Pores Formed by Amyloid Beta(25-35)
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1245
Abstract: Amyloid β (Aβ) peptide contributes to Alzheimer's disease (AD) by a yet unidentified mechanism. In brain tissue, Aβ occurs in various forms, including a undecapeptide Aβ(25-35) (GSNKGAIIGLM), which exerts neurotoxic effect through mitochondrial dysfunction and/or… read more here.
Keywords: membrane pores; biophysical characterization; pores formed; membrane ... See more keywords
Evaluation of the Hybrid Resolution Pace Model for the Study of Folding, Insertion and Pore Formation of Membrane Associated Peptides
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2836
Abstract: capacity to bind tomembranes.We also performed atomisticmolecular dynamics simulations to determine whether the first thirty N-terminal residues are able to detach from the core of the protein in its monomeric and dimeric forms and their… read more here.
Keywords: evaluation hybrid; hybrid resolution; formation; model ... See more keywords
Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2020.04.026
Abstract: Medin, a 50-amino-acid cleavage product of the milk fat globule-EGF factor 8 protein, is one of the most common forms of localized amyloid found in the vasculature of individuals older than 50 years. Medin induces… read more here.
Keywords: microscopy; medin; pore formation; pathology ... See more keywords
Fusion Pore Formation Observed during SNARE-Mediated Vesicle Fusion with Pore-Spanning Membranes.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2020.05.023
Abstract: Planar pore-spanning membranes (PSMs) have been shown to be a versatile tool to resolve elementary steps of the neuronal fusion process. However, in previous studies, we monitored only lipid mixing between fusing large unilamellar vesicles… read more here.
Keywords: pore spanning; fusion; fusion pore; pore formation ... See more keywords
Residue metals and intrinsic moisture in excess sludge improve pore formation during its carbonization process
Sign Up to like & getrecommendations! Published in 2020 at "Carbon"
DOI: 10.1016/j.carbon.2019.09.046
Abstract: Abstract Excess sludge, a carbon-rich valuable by-product from wastewater treatment, is utilized as a carbon precursor for synthesizing porous activated carbon. However, improving specific surface area (SBET) is the main challenge for the sludge derived… read more here.
Keywords: carbonization process; excess sludge; carbon; sludge ... See more keywords
Pore formation model for direct laser deposition of Al2O3–ZrO2 ceramic
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the European Ceramic Society"
DOI: 10.1016/j.jeurceramsoc.2021.09.042
Abstract: Abstract Pores are some of the most common defects that form during direct laser deposition of ceramic materials. A mathematical model of pore formation for Al2O3-ZrO2 ceramic was developed. The pore formation model, which was… read more here.
Keywords: laser deposition; laser; model; direct laser ... See more keywords
The “normalized air content”: A novel and reliable concept to assess pore formation during dehydration
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Food Engineering"
DOI: 10.1016/j.jfoodeng.2021.110733
Abstract: Abstract Porosity is generally used to monitor the evolution of pore formation during dehydration. However, in some cases of dehydration, porosity could increase without involving pore formation, resulting in misleading interpretation. To avoid this misleading… read more here.
Keywords: dehydration; air; porosity; concept ... See more keywords
Daptomycin Pore Formation Is Restricted by Lipid Acyl Chain Composition.
Sign Up to like & getrecommendations! Published in 2017 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.7b00138
Abstract: Daptomycin is a calcium-dependent lipopeptide antibiotic that is used clinically against various Gram-positive pathogens. It acts on bacterial cell membranes, whose susceptibility varies with the content of phosphatidylglycerol (PG). Some studies have reported that daptomycin… read more here.
Keywords: formation restricted; lipid acyl; restricted lipid; daptomycin ... See more keywords