Articles with "porin" as a keyword



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Regulation of the protein entry gate assembly by mitochondrial porin

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Published in 2019 at "Current Genetics"

DOI: 10.1007/s00294-019-00979-7

Abstract: Mitochondrial biogenesis and functions rely on transport of their resident proteins as well as small molecules/ions across their membranes. The TOM complex functions as a protein entry gate for most mitochondrial proteins and mitochondrial porin… read more here.

Keywords: entry gate; protein entry; mitochondrial porin; porin ... See more keywords
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Peculiarities of thermal denaturation of OmpF porin from Yersinia ruckeri.

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Published in 2017 at "Molecular bioSystems"

DOI: 10.1039/c7mb00239d

Abstract: Irreversible denaturation of membrane proteins in detergent solutions is similar to unfolding of water-soluble multidomain proteins and represents a complex, multistage process. Pore-forming proteins of Gram-negative bacteria are heat-modifiable proteins, i.e., proteins altering their molecular… read more here.

Keywords: ompf porin; porin; yersinia ruckeri; denaturation ... See more keywords
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Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates.

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Published in 2023 at "Virulence"

DOI: 10.1080/21505594.2023.2215602

Abstract: BACKGROUND Mycobacterium abscessus subspecies massiliense (M. massiliense) is increasingly recognized as an emerging bacterial pathogen, particularly in cystic fibrosis (CF) patients and CF centers' respiratory outbreaks. We characterized genomic and phenotypic changes in 15 serial… read more here.

Keywords: abscessus human; evolution mycobacterium; mycobacterium abscessus; porin ... See more keywords
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Mutational Variation Analysis of oprD Porin Gene in Multidrug-Resistant Clinical Isolates of Pseudomonas aeruginosa.

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Published in 2020 at "Microbial drug resistance"

DOI: 10.1089/mdr.2019.0147

Abstract: The present study deals with the outer membrane OprD porin protein in 29 clinical bacterial isolates of multidrug-resistant Pseudomonas aeruginosa. oprD porin gene expression was investigated using real-time reverse transcription-PCR. Amplicons from oprD and its… read more here.

Keywords: pseudomonas aeruginosa; oprd porin; porin; multidrug resistant ... See more keywords
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Mosaic Evolution of Beta-Barrel-Porin-Encoding Genes in Escherichia coli

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Published in 2022 at "Applied and Environmental Microbiology"

DOI: 10.1128/aem.00060-22

Abstract: Microevolution studies can disclose more elaborate evolutionary mechanisms of genes, appearing especially important for genes with multifaceted function such as those encoding outer membrane proteins. However, in most cases, the gene is considered as a… read more here.

Keywords: porin encoding; membrane proteins; outer membrane; mosaic evolution ... See more keywords
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Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter In Vivo Bacterial Burdens in a Murine Sepsis Model

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Published in 2022 at "Infection and Immunity"

DOI: 10.1128/iai.00176-22

Abstract: Escherichia coli is one of the most frequent human pathogens, increasingly exhibits antimicrobial resistance, and has complex interactions with the host immune system. E. coli exposure or infection can result in the generation of antibodies… read more here.

Keywords: escherichia coli; outer membrane; membrane protein; porin ... See more keywords
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Functional characterization of an N-terminally-truncated mitochondrial porin expressed in Neurospora crassa.

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Published in 2017 at "Canadian journal of microbiology"

DOI: 10.1139/cjm-2016-0764

Abstract: Mitochondrial porin, which forms voltage-dependent anion-selective channels (VDAC) in the outer membrane, can be folded into a 19-β-stranded barrel. The N terminus of the protein is external to the barrel and contains α-helical structure. Targeted… read more here.

Keywords: terminal segment; neurospora crassa; functional characterization; porin ... See more keywords
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An Abnormally High Closing Potential of the OMPF Porin Channel from Yersinia Ruckeri: The Role of Charged Residues and Intramolecular Bonds

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Published in 2019 at "Acta Naturae"

DOI: 10.32607/20758251-2019-11-3-89-98

Abstract: Electrophysiological experiments on bilayer lipid membranes showed that the isolated outer membrane major porin of Yersinia ruckeri (YrOmpF) exhibits activity typical of porins from Gram-negative bacteria, forming channels with a mean conductance of 230 pS… read more here.

Keywords: ompf porin; porin; yersinia ruckeri; channel ... See more keywords
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Increased Virulence of Outer Membrane Porin Mutants of Mycobacterium abscessus

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Published in 2021 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.706207

Abstract: Chronic pulmonary infections caused by non-tuberculous mycobacteria of the Mycobacterium abscessus complex (MABSC) are emerging as a global health problem and pose a threat to susceptible individuals with structural lung disease such as cystic fibrosis.… read more here.

Keywords: increased virulence; virulence; porin; porin mutants ... See more keywords