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Published in 2021 at "Toxicologic Pathology"
DOI: 10.1177/01926233211027474
Abstract: Porphyrinogenic compounds are known to induce porphyria-mediated hepatocellular injury and subsequent regenerative proliferation in rodents, ultimately leading to hepatocellular tumor induction. However, an appropriate in vivo experimental model to evaluate an effect of porphyrinogenic compounds…
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Keywords:
porphyria mediated;
mouse humanized;
chimeric mouse;
model ... See more keywords