Unlocking New Porphyrin Aminoacid Bioconjugates with a Pd-Catalyzed Carboxamide Synthesis.
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DOI: 10.1002/cplu.202500193
Abstract: This study introduces a novel approach for the one-step preparation of carboxamide porphyrin-amino acid bioconjugates via palladium/xantphos-catalyzed aminocarbonylation of 5,15-dibromo-10,20-diphenylporphyrin and 5,10,15,20-tetrakis(4-bromophenyl)porphyrin, under relatively mild conditions (70-100 ºC, 1 atm CO), using natural amino acid… read more here.
Keywords: porphyrin aminoacid; new porphyrin; porphyrin; amino ... See more keywords