Recombinant Porphyromonas gingivalis W83 FimA alters immune response and metabolic gene expression in oral squamous carcinoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.588
Abstract: The Gram‐negative anaerobic rod Porphyromonas gingivalis (P. gingivalis) is regarded as a keystone pathogen in periodontitis and expresses a multitude of virulence factors iincluding fimbriae that are enabling adherence to and invasion in cells and… read more here.
Keywords: expression oral; immune response; gene expression; porphyromonas gingivalis ... See more keywords
Radicular Cysts and Periapical Granulomas: Data Documentation for 696 Cases and Findings on Fibrosis, and Porphyromonas gingivalis and Fusobacterium nucleatum in These Lesions
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.70098
Abstract: The objective of our study was to re‐evaluate periapical lesions, including radicular cysts (RCs) and periapical granulomas (PGs) for locations, histopathological features, and degree of fibrosis in relation to the inflammatory response. In addition, we… read more here.
Keywords: gingivalis fusobacterium; radicular cysts; periapical granulomas; fusobacterium nucleatum ... See more keywords
Effect of xylitol on Porphyromonas gingivalis: A systematic review
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.724
Abstract: This review was conducted to assess the effectiveness of xylitol against Porphyromonas gingivalis anaerobic species, a key microbe contributing to periodontal disease pathogenesis. read more here.
Keywords: review; xylitol porphyromonas; porphyromonas gingivalis;
Regulation of calcification in human aortic smooth muscle cells infected with high‐glucose‐treated Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26268
Abstract: Porphyromonas (P.) gingivalis infection leading to the periodontitis has been associated with the development of systemic diseases, including cardiovascular diseases and diabetes. However, the effect of a high concentration of glucose (HG) on the invasion… read more here.
Keywords: infection; porphyromonas gingivalis; calcification; muscle cells ... See more keywords
Inhibitory effects of azithromycin on the adherence ability of Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.18-0559
Abstract: BACKGROUND Porphyromonas gingivalis is a major pathogen and has a high detection rate in periodontal disease. Fimbriae and hemagglutinin are expressed by P. gingivalis, and these play an important role in the adherence of the… read more here.
Keywords: porphyromonas gingivalis; mics azithromycin; sub mics; adherence ... See more keywords
Porphyromonas gingivalis and Alzheimer disease: Recent findings and potential therapies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Periodontology"
DOI: 10.1002/jper.20-0104
Abstract: Abstract Epidemiological studies have identified an association between periodontitis and Alzheimer disease (AD); however, the nature of this association has been unclear. Recent work suggests that brain colonization by the periodontal pathogen Porphyromonas gingivalis may… read more here.
Keywords: gingivalis alzheimer; porphyromonas gingivalis; alzheimer disease; disease recent ... See more keywords
Evaluation of circulating IgG antibodies against Porphyromonas gingivalis or its gingipains as serological markers of periodontitis and carriage of the bacterium
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Periodontology"
DOI: 10.1002/jper.23-0766
Abstract: Abstract Background Increasing evidence indicates that periodontitis contributes to systemic low‐grade inflammation. Porphyromonas gingivalis is strongly associated with periodontitis, and antibodies against the bacterium may be used as a serological proxy to account for periodontal… read more here.
Keywords: carriage bacterium; igg antibodies; bacterium; gingivalis ... See more keywords
Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3571
Abstract: Citrullination is an essential post‐translational modification in which the guanidinium group of protein and peptide arginines is deiminated by peptidylarginine deiminases (PADs). When deregulated, excessive citrullination leads to inflammation as in severe periodontal disease (PD)… read more here.
Keywords: ppad; variant; porphyromonas gingivalis; gingivalis ... See more keywords
Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-017-1368-4
Abstract: Background and aimsThe risk factors in the progression of nonalcoholic fatty liver disease (NAFLD) have not been fully clarified. Porphyromonas gingivalis (P.g) has been considered to be a confounding risk factor for systemic diseases. We… read more here.
Keywords: risk; fatty liver; porphyromonas gingivalis; liver disease ... See more keywords
Relationship of Porphyromonas gingivalis and Alzheimer's disease: a systematic review of pre-clinical studies.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical oral investigations"
DOI: 10.1007/s00784-020-03764-w
Abstract: OBJECTIVES This study aimed to analyze the following PICO question: Are animals infected with Porphyromonas gingivalis (P. gingivalis) or bacterial lipopolysaccharide (Pg-LPS) more affected by neurodegeneration, similar to the pathogenesis generated by Alzheimer's disease (AD), compared… read more here.
Keywords: alzheimer disease; porphyromonas gingivalis; disease; gingivalis ... See more keywords
Enhanced Responsive Formation of Extracellular Traps in Macrophages Previously Exposed to Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2022 at "Inflammation"
DOI: 10.1007/s10753-021-01611-y
Abstract: Tolerance is defined to be a hyporesponsive state following repeated stimulations with bacteria or their virulence factors and has potential impacts on the development of periodontitis. Recently, macrophages have been reported to release chromatin and… read more here.
Keywords: gingivalis; microscopy; gingivalis pretreated; pretreated macrophages ... See more keywords