Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.2210/pdb6i9e/pdb
Abstract: Double-stranded DNA viruses, including bacteriophages and herpesviruses, package their genomes into preformed capsids, using ATP-driven motors. Seeking to advance structural and mechanistic understanding, we established in vitro packaging for a thermostable bacteriophage, P23-45 of Thermus… read more here.
Keywords: dna; capsid; portal protein; dna packaging ... See more keywords
Tryptophan Residues Are Critical for Portal Protein Assembly and Incorporation in Bacteriophage P22
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DOI: 10.3390/v14071400
Abstract: The oligomerization and incorporation of the bacteriophage P22 portal protein complex into procapsids (PCs) depends upon an interaction with scaffolding protein, but the region of the portal protein that interacts with scaffolding protein has not… read more here.
Keywords: incorporation; bacteriophage p22; protein; portal protein ... See more keywords