Development of posaconazole-based analogues as hedgehog signaling pathway inhibitors.
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DOI: 10.1016/j.ejmech.2018.11.056
Abstract: Inhibition of the hedgehog (Hh) signaling pathway has been validated as a therapeutic strategy to treat basal cell carcinoma and holds potential for several other forms of human cancer. Itraconazole and posaconazole are clinically useful… read more here.
Keywords: hedgehog signaling; posaconazole based; based analogues; development posaconazole ... See more keywords