MFPS_CNN: Multi‐filter Pattern Scanning from Position‐specific Scoring Matrix with Convolutional Neural Network for Efficient Prediction of Ion Transporters
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Informatics"
DOI: 10.1002/minf.202100271
Abstract: In cellular transportation mechanisms, the movement of ions across the cell membrane and its proper control are important for cells, especially for life processes. Ion transporters/pumps and ion channel proteins work as border guards controlling… read more here.
Keywords: neural network; ion transporters; convolutional neural; ion ... See more keywords
Position‐specific 15N isotope analysis in organic molecules: A high‐precision 15N NMR method to determine the intramolecular 15N isotope composition and fractionation at natural abundance
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic Resonance in Chemistry"
DOI: 10.1002/mrc.4903
Abstract: The position‐specific 15N isotope content in organic molecules, at natural abundance, is for the first time determined by using a quantitative methodology based on 15N Nuclear Magnetic Resonance (NMR) spectrometry. 15N NMR spectra are obtained… read more here.
Keywords: methodology; isotope; 15n isotope; 15n nmr ... See more keywords
Target-DBPPred: An intelligent model for prediction of DNA-binding proteins using discrete wavelet transform based compression and light eXtreme gradient boosting.
Sign Up to like & getrecommendations! Published in 2022 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2022.105533
Abstract: DNA-protein interaction is a critical biological process that performs influential activities, including DNA transcription and recombination. DBPs (DNA-binding proteins) are closely associated with different kinds of human diseases (asthma, cancer, and AIDS), while some of… read more here.
Keywords: specific scoring; dna; extreme gradient; position specific ... See more keywords
PSSM-Suc: Accurately predicting succinylation using position specific scoring matrix into bigram for feature extraction.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2017.05.005
Abstract: Post-translational modification (PTM) is a covalent and enzymatic modification of proteins, which contributes to diversify the proteome. Despite many reported PTMs with essential roles in cellular functioning, lysine succinylation has emerged as a subject of… read more here.
Keywords: specific scoring; pssm suc; succinylation; pssm ... See more keywords
Bi-PSSM: Position specific scoring matrix based intelligent computational model for identification of mycobacterial membrane proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2017.09.013
Abstract: Mycobacterium is a pathogenic bacterium, which is a causative agent of tuberculosis (TB) and leprosy. These diseases are very crucial and become the cause of death of millions of people every year in the world.… read more here.
Keywords: computational model; specific scoring; membrane proteins; position specific ... See more keywords
Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Sign Up to like & getrecommendations! Published in 2020 at "Structure"
DOI: 10.1016/j.str.2020.07.012
Abstract: The amount of antibody (Ab) variable gene sequence information is expanding rapidly, but our ability to predict the function of Abs from sequence alone is limited. Here, we describe a sequence-to-function prediction method that couples… read more here.
Keywords: structurally related; identification structurally; structure; position specific ... See more keywords
Novel Nuclear Magnetic Resonance Method for Position-Specific Carbon Isotope Analysis of Organic Molecules with Significant Impurities.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03356
Abstract: We introduce a novel nuclear magnetic resonance (NMR) tool for determining position-specific carbon (13C/12C) isotope ratios within complex organic molecules. This analytical advancement allows us to measure position-specific isotope ratios of samples that contain impurities… read more here.
Keywords: carbon isotope; isotope; position specific; method ... See more keywords
Full Spectrum Isotopic 13C NMR Using Polarization Transfer for Position-Specific Isotope Analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02139
Abstract: For the last ten years, quantitative isotope ratio monitoring 13C NMR (irm-13C NMR) has been successfully tested and proven as an efficient tool for the determination of position-specific 13C/12C ratios. Several applications in different domains… read more here.
Keywords: position specific; 13c nmr; polarization transfer;
Computational Investigations of Position-Specific Vapor Pressure Isotope Effects in Ethanol—Toward More Powerful Isotope Models for Food Forensics
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c02446
Abstract: With the advent of new experimental techniques, measurements of individual, per-position, vapor pressure isotope effects (VPIEs) became possible. Frequently, they are in opposite directions (larger and smaller than unity), leading to the cancellation when only… read more here.
Keywords: pressure isotope; isotope; isotope effects; vapor pressure ... See more keywords
Position-specific oxidation of miR-1 encodes cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2586-0
Abstract: In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease phenotypes 1 . One such modification, 8-oxoguanine 2 (o 8 G), is abundant in RNA 3 but its epitranscriptional role has not been investigated… read more here.
Keywords: position specific; cardiac hypertrophy; mir; specific oxidation ... See more keywords
EnhancerPred2.0: predicting enhancers and their strength based on position-specific trinucleotide propensity and electron-ion interaction potential feature selection.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00054e
Abstract: Enhancers are cis-acting elements that play major roles in upregulating eukaryotic gene expression by providing binding sites for transcription factors and their complexes. Because enhancers are highly cell/tissue specific, lack common motifs, and are far… read more here.
Keywords: feature; ion interaction; electron ion; specific trinucleotide ... See more keywords