Articles with "position trnaphe" as a keyword



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The nature of the modification at position 37 of tRNAPhe correlates with acquired taxol resistance

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Published in 2020 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaa1164

Abstract: Abstract Acquired drug resistance is a major obstacle in cancer therapy. Recent studies revealed that reprogramming of tRNA modifications modulates cancer survival in response to chemotherapy. However, dynamic changes in tRNA modification were not elucidated.… read more here.

Keywords: taxol resistance; resistance; cancer; modification ... See more keywords