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   Articles with "positional effects" as a keyword



Benefits of using genomic insulators flanking transgenes to increase expression and avoid positional effects

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-44836-6

Abstract: For more than 20 years, plant biologists have tried to achieve complete control of transgene expression. Until the techniques to target transgenes to safe harbor sites in the genome become routine, flanking transgenes with genetic… read more here.

Keywords: transgene expression; avoid positional; flanking transgenes; benefits using ... See more keywords

Positional effects of electron-donating and withdrawing groups on the photophysical properties of single benzene fluorophores.

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recommendations! Published in 2024 at "Chemical communications"

DOI: 10.1039/d4cc04451g

Abstract: We investigated how the positional arrangement of electron-donating (amino) and electron-withdrawing (ester) groups in single benzene-based fluorophores influences their emission properties. By synthesizing 26 regioisomeric fluorophores, we achieved wavelength modulation from 322 to 539 nm,… read more here.

Keywords: donating withdrawing; positional effects; effects electron; electron donating ... See more keywords

Positional Effects of Fluorine Substitution on Room Temperature Phosphorescence in Hexaphenylmelamine Derivatives

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recommendations! Published in 2025 at "New Journal of Chemistry"

DOI: 10.1039/d4nj04627g

Abstract: Three hexaphenylmelamine phosphors substituted with fluorine at meta, ortho, and para positions were synthesized and characterized, showing increasing phosphorescence lifetimes and quantum yields. Crystal analysis and theoretical calculations suggest the... read more here.

Keywords: phosphorescence; positional effects; hexaphenylmelamine; effects fluorine ... See more keywords

Genetic context of transgene insertion can influence neurodevelopment in zebrafish

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recommendations! Published in 2025 at "Genetics"

DOI: 10.1093/genetics/iyaf195

Abstract: Abstract The Gal4/UAS system is used across model organisms to overexpress target genes in precise cell types and relies on generating transgenic Gal4 driver lines. In zebrafish, the Tg(elavl3:KalTA4) (HuC) Gal4 line drives robust expression… read more here.

Keywords: transgene insertion; context transgene; genetic context; positional effects ... See more keywords