Bacteria Synergized with PD‐1 Blockade Enhance Positive Feedback Loop of Cancer Cells‐M1 Macrophages‐T Cells in Glioma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202308124
Abstract: Cancer immunotherapy is an attractive strategy because it stimulates immune cells to target malignant cells by regulating the intrinsic activity of the immune system. However, due to lacking many immunologic markers, it remains difficult to… read more here.
Keywords: feedback loop; cancer; positive feedback; loop cancer ... See more keywords
Stitching the Gap: Feedback as a Mechanism for Reinforcing Sustainable Fashion Consumption
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Consumer Behaviour"
DOI: 10.1002/cb.70013
Abstract: This paper examines how positive feedback can elicit pride in sustainable fashion consumption and influence two key behavioral outcomes: willingness to buy sustainable fashion products and word‐of‐mouth endorsement. Drawing on framing theory and existing research… read more here.
Keywords: positive feedback; feedback; fashion; sustainable fashion ... See more keywords
TGF‐β1‐PML SUMOylation‐peptidyl‐prolyl cis–trans isomerase NIMA‐interacting 1 (Pin1) form a positive feedback loop to regulate cardiac fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27357
Abstract: Transforming growth factor‐β (TGF‐β) signaling pathway is involved in fibrosis in most, if not all forms of cardiac diseases. Here, we evaluate a positive feedback signaling the loop of TGF‐β1/promyelocytic leukemia (PML) SUMOylation/Pin1 promoting the… read more here.
Keywords: positive feedback; fibrosis; tgf; pml ... See more keywords
Activation of EGFR‐KLF4 positive feedback loop results in acquired resistance to sorafenib in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23102
Abstract: Sorafenib is the standard first‐line systemic chemotherapeutic drugs for advanced hepatocellular carcinoma (HCC), but acquired resistance to sorafenib is frequently observed in clinical practice. In this study, we first produced three sorafenib resistance (SR) HCC… read more here.
Keywords: positive feedback; hcc; feedback loop; sorafenib ... See more keywords
Ginsenoside Re inhibits non‐small cell lung cancer progression by suppressing macrophage M2 polarization induced by AMPKα1/STING positive feedback loop
Sign Up to like & getrecommendations! Published in 2024 at "Phytotherapy Research"
DOI: 10.1002/ptr.8309
Abstract: Tumor‐associated macrophages (TAMs) in non‐small cell lung cancer (NSCLC) promote tumor cell metastasis by interacting with cancer cells. Ginsenoside Re is capable of modulating the host immune system and exerts anticancer effects through multiple pathways.… read more here.
Keywords: feedback loop; positive feedback; sting positive; cell ... See more keywords
Sensitivity to negative and positive feedback as a stable and enduring behavioural trait in rats
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05333-w
Abstract: According to psychological theories, cognitive distortions play a pivotal role in the aetiology and recurrence of mood disorders. Although clinical evidence for the coexistence of depression and altered sensitivity to performance feedback is relatively coherent,… read more here.
Keywords: positive feedback; trait; sensitivity negative; feedback ... See more keywords
Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02678-6
Abstract: The clinical success of immune checkpoint blockade against diverse human cancers highlights the critical importance of insightful understanding into mechanisms underlying PD-L1 regulation. IFN-γ released by intratumoral lymphocytes regulates PD-L1 expression in tumor cells through… read more here.
Keywords: positive feedback; feedback loop; cancer; irf1 ... See more keywords
The effect of adolescents’ active social networking site use on life satisfaction: The sequential mediating roles of positive feedback and relational certainty
Sign Up to like & getrecommendations! Published in 2018 at "Current Psychology"
DOI: 10.1007/s12144-018-9882-y
Abstract: The present research tested the mediating roles of positive feedback and relational certainty in the relation between active social networking site use and life satisfaction. A survey research method was adopted in which four anonymous… read more here.
Keywords: positive feedback; social networking; site use; networking site ... See more keywords
MiR-135b promotes HCC tumorigenesis through a positive-feedback loop.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.008
Abstract: Hippo pathway plays critical roles in cell proliferation and apoptosis and its dysregulation leads to various types of cancers, including hepatocellular carcinoma (HCC). However, the mechanism maintaining Hippo pathway homeostasis still remains unclear. In this… read more here.
Keywords: positive feedback; mir 135b; hcc; hippo pathway ... See more keywords
Impact of Zygosity on Bimodal Phenotype Distributions.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.05.010
Abstract: Allele number, or zygosity, is a clear determinant of gene expression in diploid cells. However, the relationship between the number of copies of a gene and its expression can be hard to anticipate, especially when… read more here.
Keywords: positive feedback; gene expression; zygosity; gene ... See more keywords
Positive feedback exists and drives the glucose-mediated repression in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical journal"
DOI: 10.1016/j.bpj.2022.01.017
Abstract: The expression of the lac operon of E. coli is subject to positive feedback during growth in the presence of gratuitous inducers, but its existence in the presence of lactose remains controversial. The key question… read more here.
Keywords: induction; feedback; presence; repression ... See more keywords