A Bioinspired Lipopeptide Surmounts Therapeutic Dilemmas of Gram-Positive and Gram-Negative Polymicrobial Infection.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c10219
Abstract: Polymicrobial infections present considerable therapeutic challenges due to the absence of effective antimicrobial agents, particularly those involving both Gram-positive and Gram-negative bacteria. We hypothesize that antimicrobials rationally designed to target both the outer and inner… read more here.
Keywords: gram negative; polymicrobial infections; positive gram; gram positive ... See more keywords
Evaluation of the toxicities of silver and silver sulfide nanoparticles against Gram-positive and Gram-negative bacteria.
Sign Up to like & getrecommendations! Published in 2019 at "IET nanobiotechnology"
DOI: 10.1049/iet-nbt.2018.5221
Abstract: In this study, the endogenous lipid signalling molecules, N-myristoylethanolamine, were explored as a capping agent to synthesise stable silver nanoparticles (AgNPs) and Ag sulphide NPs (Ag2S NPs). Sulphidation of the AgNPs abolishes the surface plasmon… read more here.
Keywords: positive gram; ag2s; ag2s nps; agnps ag2s ... See more keywords
In vitro Susceptibility Testing of Essential Oils against Gram-positive and Gram-negative Clinical Isolates, including Carbapenem-resistant Enterobacteriaceae (CRE)
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.907
Abstract: Abstract Background In the era of antibiotic resistance, alternative anti-infectives must be explored. The National Action Plan for Combating Antibiotic-Resistant Bacteria calls for developing nontraditional therapeutics, including natural compounds such as essential oils (EOs) (Goal… read more here.
Keywords: gram positive; positive gram; cinnamon bark; cre ... See more keywords
Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens
Sign Up to like & getrecommendations! Published in 2024 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04234-23
Abstract: ABSTRACT Antimicrobial resistance (AMR) poses a significant worldwide public health crisis that continues to threaten our ability to successfully treat bacterial infections. With the decline in effectiveness of conventional antimicrobial therapies and the lack of… read more here.
Keywords: gram negative; bacterial pathogens; based antimicrobial; positive gram ... See more keywords
AntiBP3: A Method for Predicting Antibacterial Peptides against Gram-Positive/Negative/Variable Bacteria
Sign Up to like & getrecommendations! Published in 2024 at "Antibiotics"
DOI: 10.3390/antibiotics13020168
Abstract: Most of the existing methods developed for predicting antibacterial peptides (ABPs) are mostly designed to target either gram-positive or gram-negative bacteria. In this study, we describe a method that allows us to predict ABPs against… read more here.
Keywords: variable bacteria; positive gram; predicting antibacterial; antibacterial peptides ... See more keywords
In Vitro and In Silico Analysis of Differential Antibacterial Activity of Pomegranate Polyphenols Against Gram-Positive and Gram-Negative Bacteria
Sign Up to like & getrecommendations! Published in 2025 at "Antibiotics"
DOI: 10.3390/antibiotics14090912
Abstract: Background/Objectives: This study investigates the antimicrobial properties of pomegranate peel extract (PoPEx) and its major polyphenolic constituents against Gram-positive and Gram-negative bacteria, employing six clinical isolates of Staphylococcus aureus and five isolates of Escherichia coli.… read more here.
Keywords: gram negative; positive gram; gram positive; negative bacteria ... See more keywords
Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria
Sign Up to like & getrecommendations! Published in 2020 at "Antibiotics"
DOI: 10.3390/antibiotics9060314
Abstract: The increased resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious health concerns. This has stimulated interest in the development of bio-based therapeutics with limited resistance, namely, essential oils (EOs) or antimicrobial… read more here.
Keywords: gram positive; gram negative; negative bacteria; positive gram ... See more keywords
miRNA-Mediated Priming of Macrophage M1 Differentiation Differs in Gram-Positive and Gram-Negative Settings
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13020211
Abstract: A proper regulation of macrophage polarization is essential for the organism’s health and pathogen control. Differentiation control is known to occur at the transcriptional as well as the posttranscriptional levels. The mechanisms involved, however, have… read more here.
Keywords: gram; differentiation; gram positive; macrophage ... See more keywords
In Vitro Evaluation of the Antimicrobial Activity of Eighteen Essential Oils Against Gram-Positive and Gram-Negative Bacteria in Two Different Growth Media
Sign Up to like & getrecommendations! Published in 2025 at "Pathogens"
DOI: 10.3390/pathogens14121216
Abstract: The rise in antimicrobial resistance and tolerance over time represents a significant threat to human and animal health. This has led to a notable increase in interest within the scientific community in the development of… read more here.
Keywords: gram negative; essential oils; positive gram; gram positive ... See more keywords
In vitro evaluation of the antimicrobial efficacy of Eupatorium odoratum ethanol extract against Gram-positive and Gram-negative bacterial strains
Sign Up to like & getrecommendations! Published in 2024 at "Open Veterinary Journal"
DOI: 10.5455/ovj.2024.v14.i11.39
Abstract: Background: Eupatorium odoratum (EO) L (Siam weed) is a highly invasive species that contains various beneficial active compounds. This study was conducted to explore the antibacterial properties of EO ethanol extract against Gram-positive and Gram-negative… read more here.
Keywords: gram negative; ethanol extract; positive gram; gram positive ... See more keywords