Rs4705342 polymorphism is involved in the tumorigenesis of HBV positive HCC by altering the binding affinity of HBV induced NF‐kB with the promoter region of microRNA‐143
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DOI: 10.1002/jcb.26581
Abstract: The objective of this study was to explore the role of rs4705342 located in the miR‐143 promoter in relation to the control of HBV positive HCC and the underlying molecular mechanism. A luciferase assay was… read more here.
Keywords: mir 143; hbv positive; hbv; promoter ... See more keywords
Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection
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DOI: 10.1186/s13027-018-0179-4
Abstract: BackgroundHepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus (HBV) DNA in the liver, referred to as occult HBV… read more here.
Keywords: hcc; pre region; positive hcc; obi related ... See more keywords
FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition
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DOI: 10.3390/ijms23158305
Abstract: Alpha-fetoprotein (AFP) is an oncofetal protein that is elevated in a subset of hepatocellular carcinoma (HCC) with poor prognosis, but the molecular target activated in AFP-positive HCC remains elusive. Here, we demonstrated that the transcription… read more here.
Keywords: positive hcc; hepatocellular carcinoma; hcc; molecular target ... See more keywords