Focal adhesion alterations in G0‐positive melanoma cells
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DOI: 10.1002/cam4.5510
Abstract: Melanoma is a highly heterogeneous malignant tumor that exhibits various forms of drug resistance. Recently, reversal transition of cancer cells to the G0 phase of the cell cycle under the influence of therapeutic drugs has… read more here.
Keywords: adhesion alterations; alterations positive; melanoma; positive melanoma ... See more keywords
Use of Completion Lymph Node Dissection for Sentinel Lymph Node Positive Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2019.12.010
Abstract: BACKGROUND For patients with sentinel node positive melanoma (SNPM), randomized trials, first reported in 2015, show no benefit for routine completion lymph node dissection (CLND) in selected patients. This study examines time trends in CLND… read more here.
Keywords: node dissection; node positive; clnd; completion lymph ... See more keywords
Adoptive therapy with TCR gene-engineered T cells to treat patients with MAGE-C2-positive melanoma and head and neck cancer
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DOI: 10.1016/j.jcyt.2020.03.244
Abstract: Background & Aim We are scheduling a patient study, in which we will target the Cancer Germline Antigen MAGE-C2 (MC2), and use T cells with a young phenotype. MC2 is highly expressed in, amongst others,… read more here.
Keywords: melanoma; melanoma head; tcr; positive melanoma ... See more keywords
Nodal Recurrence is a Primary Driver of Early Relapse for Patients with Sentinel Lymph Node-Positive Melanoma in the Modern Therapeutic Era
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DOI: 10.1245/s10434-021-09804-3
Abstract: Management of patients with sentinel lymph node (SLN)-positive melanoma has changed dramatically over the last few years such that completion lymph node dissection (CLND) has become uncommon, and many patients receive adjuvant immunotherapy or targeted… read more here.
Keywords: melanoma; recurrence; relapse; positive melanoma ... See more keywords
Surveillance of Sentinel Node-Positive Melanoma Patients Who Receive Adjuvant Therapy Without Undergoing Completion Lymph Node Dissection
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DOI: 10.1245/s10434-021-10570-5
Abstract: Adjuvant therapy trials required completion lymph node dissection (CLND) for sentinel lymph node (SLN)-positive melanoma prior to systemic treatment, but nodal surveillance without CLND is now common. For patients receiving adjuvant therapy without CLND, patterns… read more here.
Keywords: lymph node; adjuvant therapy; positive melanoma; surveillance ... See more keywords