Articles with "positive modulator" as a keyword



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The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats

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Published in 2018 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2018.03.018

Abstract: &NA; S 47445 is a positive modulator of glutamate AMPA‐type receptors, possessing neurotrophic and enhancing synaptic plasticity effects as well as pro‐cognitive and anti‐stress properties. Here, the drug was assessed in the perinatal stress (PRS)… read more here.

Keywords: reduction; prs; glutamate release; positive modulator ... See more keywords