A high number of IgG4-positive plasma cells rules out nodular lymphocyte predominant Hodgkin lymphoma
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DOI: 10.1007/s00428-018-2460-8
Abstract: Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a subtype of Hodgkin lymphoma that frequently shows a nodal growth pattern with abundant reactive B cells in the microenvironment. Early NLPHL cases can be particularly difficult to… read more here.
Keywords: plasma; positive plasma; plasma cells; number ... See more keywords
Pathological characteristics and diagnosis of IgG4-related disease
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DOI: 10.1016/j.lpm.2020.104014
Abstract: Abstract IgG4-related disease (IgG4-RD) has been accepted as a distinct entity in various fields. It is being increasingly diagnosed and treated in routine practice. However, difficulties are still associated with the diagnostic process. Serum IgG4… read more here.
Keywords: igg4; related disease; positive plasma; disease ... See more keywords
Increased number of IgG4-positive plasma cells in chronic rhinosinusitis
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DOI: 10.1080/00016489.2016.1219050
Abstract: Abstract Conclusion: High levels of IgG4-positive plasma cells were observed in tissue samples from ∼30% of patients with chronic rhinosinusitis who satisfied the comprehensive diagnostic criteria for IgG4-related disease. Detection of increased numbers of IgG4-positive… read more here.
Keywords: igg4; positive plasma; rhinosinusitis; plasma cells ... See more keywords
Pediatric Eosinophilic Esophagitis Is Associated With Increased Lamina Propria Immunoglobulin G4-Positive Plasma Cells
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DOI: 10.1097/mpg.0000000000001949
Abstract: Objective: Eosinophilic esophagitis (EoE) is considered a TH2-mediated food allergy disease that leads to submucosal esophageal fibrosis and strictures. Recent studies focused on adults with EoE identified a strong association with elevated esophageal IgG4 immunostaining.… read more here.
Keywords: igg4; food allergy; positive plasma; eoe patients ... See more keywords
False-Positive Plasma Genotyping Due to Clonal Hematopoiesis
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DOI: 10.1158/1078-0432.ccr-18-0143
Abstract: Purpose: Plasma cell-free DNA (cfDNA) genotyping is increasingly used in cancer care, but assay accuracy has been debated. Because most cfDNA is derived from peripheral blood cells (PBC), we hypothesized that nonmalignant mutations harbored by… read more here.
Keywords: plasma; positive plasma; clonal hematopoiesis; false positive ... See more keywords
Clinicopathological Features of Autoimmune Hepatitis with IgG4-Positive Plasma Cell Infiltration
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DOI: 10.1159/000510562
Abstract: Background: We aimed to elucidate the characteristics and prognosis of autoimmune hepatitis (AIH) patients with immunoglobulin (Ig) G4-positive plasma cell infiltration. Methods: We enrolled 84 AIH patients. The number of IgG- and IgG4-positive plasma cells… read more here.
Keywords: positive plasma; classical aih; aih; igg4 aih ... See more keywords
Reactive Follicular Hyperplasia With Perifollicular Granulomas and Increased IgG4-Positive Plasma Cells
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DOI: 10.1177/1066896917708609
Abstract: A 47-year-old woman presented with left axillary lymphadenopathy for 2 years. Computed tomography demonstrated multiple enlarged axillary lymph nodes up to 4 cm in size. Excisional biopsy of an axillary lymph node showed reactive follicular… read more here.
Keywords: plasma; positive plasma; follicular hyperplasia; igg4 positive ... See more keywords
Glucocorticoid-dependent Tubulointerstitial Nephritis with IgM-positive Plasma Cells Presenting with Intracellular Crystalline Inclusions within the Rough Endoplasmic Reticulum.
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DOI: 10.2169/internalmedicine.7118-21
Abstract: Tubulointerstitial nephritis (TIN) with IgM-positive plasma cells (IgMPC-TIN) is an autoimmune kidney disease characterized by IgM/CD138-double-positive plasma cell infiltration in the tubulointerstitium. A 50-year-old man developed IgMPC-TIN and presented with crystalline inclusions in the rough… read more here.
Keywords: igm positive; positive plasma; tubulointerstitial nephritis; tin ... See more keywords